{"title":"回顾艾氯胺酮对难治性抑郁症的持续疗效","authors":"","doi":"10.1002/pu.31310","DOIUrl":null,"url":null,"abstract":"<p>Results of a systematic review and meta-analysis suggest that esketamine has only modest efficacy in the treatment of adults with treatment-resistant depression, with initial improvement diminishing after the first few days. The results also suggest no effect of esketamine on suicidality.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 6","pages":"3"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Review questions sustained efficacy of esketamine in treatment-resistant depression\",\"authors\":\"\",\"doi\":\"10.1002/pu.31310\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Results of a systematic review and meta-analysis suggest that esketamine has only modest efficacy in the treatment of adults with treatment-resistant depression, with initial improvement diminishing after the first few days. The results also suggest no effect of esketamine on suicidality.</p>\",\"PeriodicalId\":22275,\"journal\":{\"name\":\"The Brown University Psychopharmacology Update\",\"volume\":\"36 6\",\"pages\":\"3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Brown University Psychopharmacology Update\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/pu.31310\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31310","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Review questions sustained efficacy of esketamine in treatment-resistant depression
Results of a systematic review and meta-analysis suggest that esketamine has only modest efficacy in the treatment of adults with treatment-resistant depression, with initial improvement diminishing after the first few days. The results also suggest no effect of esketamine on suicidality.
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