A. Ripanda , A.A. Nyundo , E.C. Nyanza , B.B.L. Srivastava , M. Hossein , R. Bakari , S.A.H. Vuai
{"title":"新型精神活性物质流行病:非洲青年探索的隐藏危险","authors":"A. Ripanda , A.A. Nyundo , E.C. Nyanza , B.B.L. Srivastava , M. Hossein , R. Bakari , S.A.H. Vuai","doi":"10.1016/j.jemep.2025.101111","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The swift rise of Novel Psychoactive Substances (NPS) is a salient, yet pressing public health and equity challenge in Africa, disproportionately impacting young people. These \"designer drugs\" or \"legal highs\" are synthetically engineered to imitate the effects of traditional narcotics while evading present legal controls. The unregulated nature of these substances exposes users to untested and potentially harmful compounds, posing significant health risks to users. The easy accessibility, through online platforms and local dealers, coupled with limited public awareness, exacerbates the crisis. This growing epidemic highlights deep systemic inequities, including gaps in African healthcare systems and regulatory frameworks, which struggle to address NPS-related health issues or keep pace with the relentless emergence of new substances, leaving vulnerable populations at heightened risk.</div></div><div><h3>Results</h3><div>The rise of NPS in Africa reveals a complex and escalating crisis, particularly affecting the youth. These substances, marketed as legal or safer alternatives to traditional drugs, are easily accessible through online platforms and local dealers, yet their volatile chemical compositions, presumed safety and legality pose significant health risks, including poisoning, addiction potential, and long-term neurotoxicity. The hasty evolution of NPS structures outpaces regulatory frameworks, leaving law enforcement and public health systems struggling to respond effectively. Limited awareness among users, coupled with socioeconomic drivers like poverty and unemployment, exacerbates the issue, while healthcare systems remain ill-equipped to manage NPS-related emergencies due to a lack of state of art diagnostic tools and treatment protocols. The emerging links to organized crime, which amplify the challenge of controlling, production, and trafficking of NPS compounds.</div></div><div><h3>Conclusion</h3><div>The NPS epidemic has aggravated health and equity challenges among youth, leading to a surge in adverse health outcomes including erratic reactions, addiction, and potential progression to more injurious substances especially in low resource settings. Tackling the NPS crisis in Africa requires equity-focused effort involving governments, international organizations, and local stakeholders. This may include public education, stricter regulation, regional cooperation, prevention, harm reduction, stewardships, and robust healthcare interventions to safeguard Africa’s youth. Further, ensuring equitable access to resources, education, and support will help curb the spread of harmful substances and protect vulnerable youth from the disproportionate health and social impacts of this growing epidemic.</div></div>","PeriodicalId":37707,"journal":{"name":"Ethics, Medicine and Public Health","volume":"33 ","pages":"Article 101111"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Novel Psychoactive Substances epidemic: The hidden perils of youthful exploration in Africa\",\"authors\":\"A. Ripanda , A.A. Nyundo , E.C. Nyanza , B.B.L. Srivastava , M. Hossein , R. Bakari , S.A.H. Vuai\",\"doi\":\"10.1016/j.jemep.2025.101111\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>The swift rise of Novel Psychoactive Substances (NPS) is a salient, yet pressing public health and equity challenge in Africa, disproportionately impacting young people. These \\\"designer drugs\\\" or \\\"legal highs\\\" are synthetically engineered to imitate the effects of traditional narcotics while evading present legal controls. The unregulated nature of these substances exposes users to untested and potentially harmful compounds, posing significant health risks to users. The easy accessibility, through online platforms and local dealers, coupled with limited public awareness, exacerbates the crisis. This growing epidemic highlights deep systemic inequities, including gaps in African healthcare systems and regulatory frameworks, which struggle to address NPS-related health issues or keep pace with the relentless emergence of new substances, leaving vulnerable populations at heightened risk.</div></div><div><h3>Results</h3><div>The rise of NPS in Africa reveals a complex and escalating crisis, particularly affecting the youth. These substances, marketed as legal or safer alternatives to traditional drugs, are easily accessible through online platforms and local dealers, yet their volatile chemical compositions, presumed safety and legality pose significant health risks, including poisoning, addiction potential, and long-term neurotoxicity. The hasty evolution of NPS structures outpaces regulatory frameworks, leaving law enforcement and public health systems struggling to respond effectively. Limited awareness among users, coupled with socioeconomic drivers like poverty and unemployment, exacerbates the issue, while healthcare systems remain ill-equipped to manage NPS-related emergencies due to a lack of state of art diagnostic tools and treatment protocols. The emerging links to organized crime, which amplify the challenge of controlling, production, and trafficking of NPS compounds.</div></div><div><h3>Conclusion</h3><div>The NPS epidemic has aggravated health and equity challenges among youth, leading to a surge in adverse health outcomes including erratic reactions, addiction, and potential progression to more injurious substances especially in low resource settings. Tackling the NPS crisis in Africa requires equity-focused effort involving governments, international organizations, and local stakeholders. This may include public education, stricter regulation, regional cooperation, prevention, harm reduction, stewardships, and robust healthcare interventions to safeguard Africa’s youth. Further, ensuring equitable access to resources, education, and support will help curb the spread of harmful substances and protect vulnerable youth from the disproportionate health and social impacts of this growing epidemic.</div></div>\",\"PeriodicalId\":37707,\"journal\":{\"name\":\"Ethics, Medicine and Public Health\",\"volume\":\"33 \",\"pages\":\"Article 101111\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ethics, Medicine and Public Health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2352552525000702\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ethics, Medicine and Public Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352552525000702","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Novel Psychoactive Substances epidemic: The hidden perils of youthful exploration in Africa
Background
The swift rise of Novel Psychoactive Substances (NPS) is a salient, yet pressing public health and equity challenge in Africa, disproportionately impacting young people. These "designer drugs" or "legal highs" are synthetically engineered to imitate the effects of traditional narcotics while evading present legal controls. The unregulated nature of these substances exposes users to untested and potentially harmful compounds, posing significant health risks to users. The easy accessibility, through online platforms and local dealers, coupled with limited public awareness, exacerbates the crisis. This growing epidemic highlights deep systemic inequities, including gaps in African healthcare systems and regulatory frameworks, which struggle to address NPS-related health issues or keep pace with the relentless emergence of new substances, leaving vulnerable populations at heightened risk.
Results
The rise of NPS in Africa reveals a complex and escalating crisis, particularly affecting the youth. These substances, marketed as legal or safer alternatives to traditional drugs, are easily accessible through online platforms and local dealers, yet their volatile chemical compositions, presumed safety and legality pose significant health risks, including poisoning, addiction potential, and long-term neurotoxicity. The hasty evolution of NPS structures outpaces regulatory frameworks, leaving law enforcement and public health systems struggling to respond effectively. Limited awareness among users, coupled with socioeconomic drivers like poverty and unemployment, exacerbates the issue, while healthcare systems remain ill-equipped to manage NPS-related emergencies due to a lack of state of art diagnostic tools and treatment protocols. The emerging links to organized crime, which amplify the challenge of controlling, production, and trafficking of NPS compounds.
Conclusion
The NPS epidemic has aggravated health and equity challenges among youth, leading to a surge in adverse health outcomes including erratic reactions, addiction, and potential progression to more injurious substances especially in low resource settings. Tackling the NPS crisis in Africa requires equity-focused effort involving governments, international organizations, and local stakeholders. This may include public education, stricter regulation, regional cooperation, prevention, harm reduction, stewardships, and robust healthcare interventions to safeguard Africa’s youth. Further, ensuring equitable access to resources, education, and support will help curb the spread of harmful substances and protect vulnerable youth from the disproportionate health and social impacts of this growing epidemic.
期刊介绍:
This review aims to compare approaches to medical ethics and bioethics in two forms, Anglo-Saxon (Ethics, Medicine and Public Health) and French (Ethique, Médecine et Politiques Publiques). Thus, in their native languages, the authors will present research on the legitimacy of the practice and appreciation of the consequences of acts towards patients as compared to the limits acceptable by the community, as illustrated by the democratic debate.