新型1,2,3-三唑悬垂型2-苯乙烯基色素衍生物的合成及抑菌活性研究

IF 0.9 4区化学 Q4 CHEMISTRY, MULTIDISCIPLINARY

Russian Journal of General Chemistry Pub Date : 2025-04-25 DOI:10.1134/S1070363224610810

P. Limbadri, Y. Hemasri, Y. Jayaprakash Rao

{"title":"新型1,2,3-三唑悬垂型2-苯乙烯基色素衍生物的合成及抑菌活性研究","authors":"P. Limbadri, Y. Hemasri, Y. Jayaprakash Rao","doi":"10.1134/S1070363224610810","DOIUrl":null,"url":null,"abstract":"A new series of 1,2,3-triazole tethered 2-styrylchromone derivatives were synthesized by adopting a simple and efficient regioselective Cu(I) catalyzed 1,3-dipolar cycloaddition reaction of corresponding 3-O-propargyl 2-styrylchromone with various aryl azides. The synthesized compounds were characterized using 1H, 13C NMR, HRMS and mass spectrometry and were screened for their antibacterial activity. Two representatives of synthesized dihalogen-substituted compounds showed good activity.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 4","pages":"824 - 832"},"PeriodicalIF":0.9000,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis and Antibacterial Activity of Novel 1,2,3-Triazole Pendant 2-Styrylchromone Derivatives\",\"authors\":\"P. Limbadri, Y. Hemasri, Y. Jayaprakash Rao\",\"doi\":\"10.1134/S1070363224610810\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A new series of 1,2,3-triazole tethered 2-styrylchromone derivatives were synthesized by adopting a simple and efficient regioselective Cu(I) catalyzed 1,3-dipolar cycloaddition reaction of corresponding 3-O-propargyl 2-styrylchromone with various aryl azides. The synthesized compounds were characterized using 1H, 13C NMR, HRMS and mass spectrometry and were screened for their antibacterial activity. Two representatives of synthesized dihalogen-substituted compounds showed good activity.\",\"PeriodicalId\":761,\"journal\":{\"name\":\"Russian Journal of General Chemistry\",\"volume\":\"95 4\",\"pages\":\"824 - 832\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-04-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of General Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1070363224610810\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of General Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1070363224610810","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

采用Cu(I)催化的1,3- o -丙炔基2-苯基铬酮与各种芳基叠氮化合物进行简单高效的区域选择性加成反应，合成了一系列新的1,2,3-三唑系2-苯基铬酮衍生物。利用1H、13C NMR、HRMS和质谱对合成的化合物进行了表征，并对其抗菌活性进行了筛选。合成的两种双卤代化合物具有良好的活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Synthesis and Antibacterial Activity of Novel 1,2,3-Triazole Pendant 2-Styrylchromone Derivatives

查看原文本刊更多论文

Synthesis and Antibacterial Activity of Novel 1,2,3-Triazole Pendant 2-Styrylchromone Derivatives

A new series of 1,2,3-triazole tethered 2-styrylchromone derivatives were synthesized by adopting a simple and efficient regioselective Cu(I) catalyzed 1,3-dipolar cycloaddition reaction of corresponding 3-O-propargyl 2-styrylchromone with various aryl azides. The synthesized compounds were characterized using ¹H, ¹³C NMR, HRMS and mass spectrometry and were screened for their antibacterial activity. Two representatives of synthesized dihalogen-substituted compounds showed good activity.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Russian Journal of General Chemistry 化学-化学综合

CiteScore

1.40

自引率

22.20%

发文量

252

审稿时长

2-4 weeks

期刊介绍： Russian Journal of General Chemistry is a journal that covers many problems that are of general interest to the whole community of chemists. The journal is the successor to Russia’s first chemical journal, Zhurnal Russkogo Khimicheskogo Obshchestva (Journal of the Russian Chemical Society ) founded in 1869 to cover all aspects of chemistry. Now the journal is focused on the interdisciplinary areas of chemistry (organometallics, organometalloids, organoinorganic complexes, mechanochemistry, nanochemistry, etc.), new achievements and long-term results in the field. The journal publishes reviews, current scientific papers, letters to the editor, and discussion papers.