{"title":"Ormosil在生物传感中的性能及应用","authors":"Purnima Justa, Nancy Jaswal, Deeksha Rana, Hemant Kumar, Neha Yadav, Vijay Bahadur, Pramod Kumar","doi":"10.1007/s12633-025-03256-0","DOIUrl":null,"url":null,"abstract":"<div><p>Ormosil, known for its unique attributes such as tuneable porosity, ability to possess a high amount of exposed surface area relative to their volume, and compatibility with living organisms, is promising as a biosensor material. This review covers current advances, methods, and obstacles associated with the use of Ormosil-based biosensors for the recognition of various analytes, including biomolecules, ions, and gases. Synthesis methods specifically tailored to biosensing are discussed, with an emphasis on strategies to brush up the sensitivity, selectivity, and stability of the sensors. It concludes by outlining prospects and challenges, emphasizing the potential of Ormosil-based biosensors in healthcare, environmental monitoring, industrial control processes, drug delivery and food safety. It highlights the need for interdisciplinary collaboration and innovative approaches to overcome current limitations and fully exploit Ormosil's capabilities in biosensor applications.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":776,"journal":{"name":"Silicon","volume":"17 5","pages":"953 - 979"},"PeriodicalIF":2.8000,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Properties and Applications of Ormosil for Biosensing\",\"authors\":\"Purnima Justa, Nancy Jaswal, Deeksha Rana, Hemant Kumar, Neha Yadav, Vijay Bahadur, Pramod Kumar\",\"doi\":\"10.1007/s12633-025-03256-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Ormosil, known for its unique attributes such as tuneable porosity, ability to possess a high amount of exposed surface area relative to their volume, and compatibility with living organisms, is promising as a biosensor material. This review covers current advances, methods, and obstacles associated with the use of Ormosil-based biosensors for the recognition of various analytes, including biomolecules, ions, and gases. Synthesis methods specifically tailored to biosensing are discussed, with an emphasis on strategies to brush up the sensitivity, selectivity, and stability of the sensors. It concludes by outlining prospects and challenges, emphasizing the potential of Ormosil-based biosensors in healthcare, environmental monitoring, industrial control processes, drug delivery and food safety. It highlights the need for interdisciplinary collaboration and innovative approaches to overcome current limitations and fully exploit Ormosil's capabilities in biosensor applications.</p><h3>Graphical Abstract</h3>\\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":776,\"journal\":{\"name\":\"Silicon\",\"volume\":\"17 5\",\"pages\":\"953 - 979\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-02-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Silicon\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s12633-025-03256-0\",\"RegionNum\":3,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Silicon","FirstCategoryId":"88","ListUrlMain":"https://link.springer.com/article/10.1007/s12633-025-03256-0","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
Properties and Applications of Ormosil for Biosensing
Ormosil, known for its unique attributes such as tuneable porosity, ability to possess a high amount of exposed surface area relative to their volume, and compatibility with living organisms, is promising as a biosensor material. This review covers current advances, methods, and obstacles associated with the use of Ormosil-based biosensors for the recognition of various analytes, including biomolecules, ions, and gases. Synthesis methods specifically tailored to biosensing are discussed, with an emphasis on strategies to brush up the sensitivity, selectivity, and stability of the sensors. It concludes by outlining prospects and challenges, emphasizing the potential of Ormosil-based biosensors in healthcare, environmental monitoring, industrial control processes, drug delivery and food safety. It highlights the need for interdisciplinary collaboration and innovative approaches to overcome current limitations and fully exploit Ormosil's capabilities in biosensor applications.
期刊介绍:
The journal Silicon is intended to serve all those involved in studying the role of silicon as an enabling element in materials science. There are no restrictions on disciplinary boundaries provided the focus is on silicon-based materials or adds significantly to the understanding of such materials. Accordingly, such contributions are welcome in the areas of inorganic and organic chemistry, physics, biology, engineering, nanoscience, environmental science, electronics and optoelectronics, and modeling and theory. Relevant silicon-based materials include, but are not limited to, semiconductors, polymers, composites, ceramics, glasses, coatings, resins, composites, small molecules, and thin films.