Afsaneh Abareshi, Mohammad Mahdi Shahidi, Nasrin Salehi
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引用次数: 0
摘要
本研究的目的是评估新型二硫化钼（MoS2）基纳米复合材料在光热治疗中的潜力。为此，通过将MoS2悬浮液分别与cu和aunr物理混合，合成了MoS2- cu （MoCS）和MoS2- aunr （MoAu）纳米复合材料。利用x射线衍射（XRD）、透射电子显微镜（TEM）、紫外可见光谱（UV-Vis）和傅里叶变换红外光谱（FTIR）对纳米复合材料的结构和光学性能进行了表征。在功率密度为1 W/cm2的近红外（NIR）辐射10 min下，对纳米复合材料的光热性能进行了评估。结果表明，MoCS和MoAu纳米复合材料的光热加热能力都比各自的组分强。此外，MoAu纳米复合材料比MoCS纳米复合材料产生更高的光热。这些发现表明MoCS和MoAu纳米复合材料具有作为新型光热剂治疗癌症的强大潜力。图形抽象
Comparison of structural, optical, and thermal properties in MoS2 based nanocomposites into cancer therapy
The objective of the present study is to evaluate the potential of novel molybdenum disulfide (MoS2)-based nanocomposites for photothermal therapy. For this purpose, MoS2-CuS (MoCS) and MoS2-AuNR (MoAu) nanocomposites were synthesized by physically mixing MoS2 suspensions with CuS and AuNRs, respectively. The structural and optical properties of these nanocomposites were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), ultraviolet-visible (UV–Vis) spectroscopy, and Fourier transform infrared (FTIR) spectroscopy. The photothermal performance of the nanocomposites was assessed under near-infrared (NIR) radiation at a power density of 1 W/cm2 for 10 min. The results demonstrated that both MoCS and MoAu nanocomposites exhibited enhanced photothermal heating compared to their individual components. Furthermore, the MoAu nanocomposite generated higher photothermal heat than the MoCS nanocomposite. These findings suggest that the MoCS and MoAu nanocomposites have strong potential as novel photothermal agents for cancer therapy.
期刊介绍：
The Journal of Materials Science: Materials in Medicine publishes refereed papers providing significant progress in the application of biomaterials and tissue engineering constructs as medical or dental implants, prostheses and devices. Coverage spans a wide range of topics from basic science to clinical applications, around the theme of materials in medicine and dentistry. The central element is the development of synthetic and natural materials used in orthopaedic, maxillofacial, cardiovascular, neurological, ophthalmic and dental applications. Special biomedical topics include biomaterial synthesis and characterisation, biocompatibility studies, nanomedicine, tissue engineering constructs and cell substrates, regenerative medicine, computer modelling and other advanced experimental methodologies.
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