A difficult case of treatment for lower lip bite wound in Moebius syndrome: A case report

Moebius syndrome (MS) is a rare, non-progressive, congenital neuromuscular disease that affects the oral and maxillofacial region. MS is characterized by bilateral or unilateral palsy of the abducens and facial nerves, specifically cranial nerves VI and VII. Orofacial manifestations include facial weakness, a hypoplastic upper lip, microstomia, dropping corners of the mouth, mandibular hypoplasia, a high-arched palate, tongue malformation, and an open bite.

Here, we present a case of repeated lower lip bite wounds in a patient with MS. In addition, severe luxation of a primary tooth, self-inflicted palate injuries, and tongue-bite wounds were observed. However, this case was particularly difficult to treat. Despite the diverse oral features reported in Moebius syndrome, oral trauma due to self-injury is rare.