Mousumi Ghosh , Hari Prakash Palaniswamy , Nishitha. G , Stelyna Joylin , Shwetha. T.S , M. Sanjana , R.P. Radhika , Nagarajan Theruveethi
{"title":"家用白光LED对健康成人认知功能的影响及蓝阻晶状体的改善","authors":"Mousumi Ghosh , Hari Prakash Palaniswamy , Nishitha. G , Stelyna Joylin , Shwetha. T.S , M. Sanjana , R.P. Radhika , Nagarajan Theruveethi","doi":"10.1016/j.nbscr.2025.100119","DOIUrl":null,"url":null,"abstract":"<div><div>White light-emitting diodes <strong>(</strong>WLEDs) can affect cognition and working memory. Blue light-blocking lenses (BBL) may help alleviate this. We aim to study the relationship between WLED and the ameliorative effect of BBL. We included 15 healthy participants based on the PSQI and Mini-Cog™ screening. The eligible participants underwent a baseline recording of event-related potential (ERP) of P300 using electroencephalography (EEG) while performing a 2-back task, followed by exposure to WLED (600 lux) that was given (45° with 80 cm apart from the participant's eye plane) for 30 min. A similar protocol was maintained when BBL was worn with WLED exposure. The participants' mean PSQI and Mini-Cog™ scores (n = 15) were 3 and 5, respectively. The behavioral functioning of participants using a 2-back task revealed enhancement in working memory cognition by fastening the response time (ms) from base to post-WLED to post-WLED + BBL (p < 0.001). Still, no significant difference (p > 0.05) in accuracy (%) was observed. The learning effect in the control group using a 2-back task revealed no statistically significant difference (p > 0.05) in both accuracy (%) and response time (ms). Additionally, no significant change (p > 0.05) was found within the three light groups in latency (ms) and amplitude (μV) at the P300 region of ERP in the prefrontal cortex. The existing results found that domestic WLED exposure significantly leads to a faster response time in working memory performance in the prefrontal cortex, thus remaining alert. BBL is not protective in the nonvisual senses when exposed to WLED for 30 min.</div></div>","PeriodicalId":37827,"journal":{"name":"Neurobiology of Sleep and Circadian Rhythms","volume":"18 ","pages":"Article 100119"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of domestic white LED light on cognitive functions and amelioration of blue light blocking lens (BBL) on healthy adults\",\"authors\":\"Mousumi Ghosh , Hari Prakash Palaniswamy , Nishitha. G , Stelyna Joylin , Shwetha. T.S , M. Sanjana , R.P. Radhika , Nagarajan Theruveethi\",\"doi\":\"10.1016/j.nbscr.2025.100119\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>White light-emitting diodes <strong>(</strong>WLEDs) can affect cognition and working memory. Blue light-blocking lenses (BBL) may help alleviate this. We aim to study the relationship between WLED and the ameliorative effect of BBL. We included 15 healthy participants based on the PSQI and Mini-Cog™ screening. The eligible participants underwent a baseline recording of event-related potential (ERP) of P300 using electroencephalography (EEG) while performing a 2-back task, followed by exposure to WLED (600 lux) that was given (45° with 80 cm apart from the participant's eye plane) for 30 min. A similar protocol was maintained when BBL was worn with WLED exposure. The participants' mean PSQI and Mini-Cog™ scores (n = 15) were 3 and 5, respectively. The behavioral functioning of participants using a 2-back task revealed enhancement in working memory cognition by fastening the response time (ms) from base to post-WLED to post-WLED + BBL (p < 0.001). Still, no significant difference (p > 0.05) in accuracy (%) was observed. The learning effect in the control group using a 2-back task revealed no statistically significant difference (p > 0.05) in both accuracy (%) and response time (ms). Additionally, no significant change (p > 0.05) was found within the three light groups in latency (ms) and amplitude (μV) at the P300 region of ERP in the prefrontal cortex. The existing results found that domestic WLED exposure significantly leads to a faster response time in working memory performance in the prefrontal cortex, thus remaining alert. BBL is not protective in the nonvisual senses when exposed to WLED for 30 min.</div></div>\",\"PeriodicalId\":37827,\"journal\":{\"name\":\"Neurobiology of Sleep and Circadian Rhythms\",\"volume\":\"18 \",\"pages\":\"Article 100119\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neurobiology of Sleep and Circadian Rhythms\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2451994425000082\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurobiology of Sleep and Circadian Rhythms","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2451994425000082","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Impact of domestic white LED light on cognitive functions and amelioration of blue light blocking lens (BBL) on healthy adults
White light-emitting diodes (WLEDs) can affect cognition and working memory. Blue light-blocking lenses (BBL) may help alleviate this. We aim to study the relationship between WLED and the ameliorative effect of BBL. We included 15 healthy participants based on the PSQI and Mini-Cog™ screening. The eligible participants underwent a baseline recording of event-related potential (ERP) of P300 using electroencephalography (EEG) while performing a 2-back task, followed by exposure to WLED (600 lux) that was given (45° with 80 cm apart from the participant's eye plane) for 30 min. A similar protocol was maintained when BBL was worn with WLED exposure. The participants' mean PSQI and Mini-Cog™ scores (n = 15) were 3 and 5, respectively. The behavioral functioning of participants using a 2-back task revealed enhancement in working memory cognition by fastening the response time (ms) from base to post-WLED to post-WLED + BBL (p < 0.001). Still, no significant difference (p > 0.05) in accuracy (%) was observed. The learning effect in the control group using a 2-back task revealed no statistically significant difference (p > 0.05) in both accuracy (%) and response time (ms). Additionally, no significant change (p > 0.05) was found within the three light groups in latency (ms) and amplitude (μV) at the P300 region of ERP in the prefrontal cortex. The existing results found that domestic WLED exposure significantly leads to a faster response time in working memory performance in the prefrontal cortex, thus remaining alert. BBL is not protective in the nonvisual senses when exposed to WLED for 30 min.
期刊介绍:
Neurobiology of Sleep and Circadian Rhythms is a multidisciplinary journal for the publication of original research and review articles on basic and translational research into sleep and circadian rhythms. The journal focuses on topics covering the mechanisms of sleep/wake and circadian regulation from molecular to systems level, and on the functional consequences of sleep and circadian disruption. A key aim of the journal is the translation of basic research findings to understand and treat sleep and circadian disorders. Topics include, but are not limited to: Basic and translational research, Molecular mechanisms, Genetics and epigenetics, Inflammation and immunology, Memory and learning, Neurological and neurodegenerative diseases, Neuropsychopharmacology and neuroendocrinology, Behavioral sleep and circadian disorders, Shiftwork, Social jetlag.