{"title":"医疗保健应用中基于mxene的电化学传感器的最新进展","authors":"Harini Loganathan , Durgalakshmi Dhinasekaran , Ajay Rakkesh Rajendran","doi":"10.1016/j.trac.2025.118276","DOIUrl":null,"url":null,"abstract":"<div><div>MXenes, a class of two-dimensional (2D) transition metal carbides, nitrides, and carbonitrides, have garnered substantial attention due to their remarkable electrochemical properties synthesized via top-down and bottom-up approaches. The rapid advancement of electrochemical sensing technology inspires the development of innovative sensing platforms for healthcare applications. This review focuses on recent breakthroughs in MXene based electrochemical sensors, imposing their exceptional conductivity and surface area. We highlight scalable key synthesis methods, properties, and unique features of MXenes that make them promising materials for sensing applications. We discuss fabrication techniques and functionalization strategies for sensor optimization as MXene sensors provide versatile healthcare applications, including diagnostics and real-time monitoring. This review also emphasizes on the development of point of care devices integrated with machine learning for prompt accurate results. This review concludes by discussing current challenges and future prospects for advancing MXene-based electrochemical sensors for healthcare applications using machine learning aspects.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":"189 ","pages":"Article 118276"},"PeriodicalIF":11.8000,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Recent advances in MXene-based electrochemical sensors for healthcare applications\",\"authors\":\"Harini Loganathan , Durgalakshmi Dhinasekaran , Ajay Rakkesh Rajendran\",\"doi\":\"10.1016/j.trac.2025.118276\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>MXenes, a class of two-dimensional (2D) transition metal carbides, nitrides, and carbonitrides, have garnered substantial attention due to their remarkable electrochemical properties synthesized via top-down and bottom-up approaches. The rapid advancement of electrochemical sensing technology inspires the development of innovative sensing platforms for healthcare applications. This review focuses on recent breakthroughs in MXene based electrochemical sensors, imposing their exceptional conductivity and surface area. We highlight scalable key synthesis methods, properties, and unique features of MXenes that make them promising materials for sensing applications. We discuss fabrication techniques and functionalization strategies for sensor optimization as MXene sensors provide versatile healthcare applications, including diagnostics and real-time monitoring. This review also emphasizes on the development of point of care devices integrated with machine learning for prompt accurate results. This review concludes by discussing current challenges and future prospects for advancing MXene-based electrochemical sensors for healthcare applications using machine learning aspects.</div></div>\",\"PeriodicalId\":439,\"journal\":{\"name\":\"Trends in Analytical Chemistry\",\"volume\":\"189 \",\"pages\":\"Article 118276\"},\"PeriodicalIF\":11.8000,\"publicationDate\":\"2025-04-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Analytical Chemistry\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S016599362500144X\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S016599362500144X","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Recent advances in MXene-based electrochemical sensors for healthcare applications
MXenes, a class of two-dimensional (2D) transition metal carbides, nitrides, and carbonitrides, have garnered substantial attention due to their remarkable electrochemical properties synthesized via top-down and bottom-up approaches. The rapid advancement of electrochemical sensing technology inspires the development of innovative sensing platforms for healthcare applications. This review focuses on recent breakthroughs in MXene based electrochemical sensors, imposing their exceptional conductivity and surface area. We highlight scalable key synthesis methods, properties, and unique features of MXenes that make them promising materials for sensing applications. We discuss fabrication techniques and functionalization strategies for sensor optimization as MXene sensors provide versatile healthcare applications, including diagnostics and real-time monitoring. This review also emphasizes on the development of point of care devices integrated with machine learning for prompt accurate results. This review concludes by discussing current challenges and future prospects for advancing MXene-based electrochemical sensors for healthcare applications using machine learning aspects.
期刊介绍:
TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.