Johannes Koren , Kady Colabrese , Manfred Hartmann , Moritz Feigl , Clemens Lang , Sebastian Hafner , Nicolas Nierenberg , Tilmann Kluge , Christoph Baumgartner
{"title":"商用查封检测软件的系统比较:更新等于升级?","authors":"Johannes Koren , Kady Colabrese , Manfred Hartmann , Moritz Feigl , Clemens Lang , Sebastian Hafner , Nicolas Nierenberg , Tilmann Kluge , Christoph Baumgartner","doi":"10.1016/j.clinph.2025.04.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To compare two updated commercially available seizure detection software packages (encevis 2.0 and Persyst 14) in a large video-EEG monitoring dataset comprising 80 patients with 6826 h of EEG and 912 seizures.</div></div><div><h3>Methods</h3><div>We conducted a follow up study of two seizure detection software packages with a significant update since 2021 using different sensitivity settings.</div></div><div><h3>Results</h3><div>Mean overall seizure count was 11.4 and mean tonic-clonic seizure rate was 0.7 per patient. Detection rates (DR) per patient were 80.7% to 89.1% for encevis 2.0 and 67.3% to 71.1% for Persyst 14. False positive rates (FPR) per day were 12 to 22 for encevis 2.0 and 2 to 4 for Persyst 14.</div></div><div><h3>Conclusions</h3><div>Encevis 2.0 showed a significantly higher DR than Persyst 14, whereas Persyst 14 showed a significantly lower FPR than encevis 2.0.</div></div><div><h3>Significance</h3><div>Updated FDA and CE certified seizure detection software showed opposite changes: encevis improved in sensitivity and deteriorated in FPR, while Persyst improved in FPR and deteriorated in sensitivity. In agreement with previous publications, automatic seizure detection software is ready for routine clinical use, but specialized personnel with sound neurophysiological knowledge and awareness of the strengths and weaknesses of the specific software package used is critical.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"174 ","pages":"Pages 178-188"},"PeriodicalIF":3.7000,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Systematic comparison of Commercial seizure detection Software: Update equals Upgrade?\",\"authors\":\"Johannes Koren , Kady Colabrese , Manfred Hartmann , Moritz Feigl , Clemens Lang , Sebastian Hafner , Nicolas Nierenberg , Tilmann Kluge , Christoph Baumgartner\",\"doi\":\"10.1016/j.clinph.2025.04.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>To compare two updated commercially available seizure detection software packages (encevis 2.0 and Persyst 14) in a large video-EEG monitoring dataset comprising 80 patients with 6826 h of EEG and 912 seizures.</div></div><div><h3>Methods</h3><div>We conducted a follow up study of two seizure detection software packages with a significant update since 2021 using different sensitivity settings.</div></div><div><h3>Results</h3><div>Mean overall seizure count was 11.4 and mean tonic-clonic seizure rate was 0.7 per patient. Detection rates (DR) per patient were 80.7% to 89.1% for encevis 2.0 and 67.3% to 71.1% for Persyst 14. False positive rates (FPR) per day were 12 to 22 for encevis 2.0 and 2 to 4 for Persyst 14.</div></div><div><h3>Conclusions</h3><div>Encevis 2.0 showed a significantly higher DR than Persyst 14, whereas Persyst 14 showed a significantly lower FPR than encevis 2.0.</div></div><div><h3>Significance</h3><div>Updated FDA and CE certified seizure detection software showed opposite changes: encevis improved in sensitivity and deteriorated in FPR, while Persyst improved in FPR and deteriorated in sensitivity. In agreement with previous publications, automatic seizure detection software is ready for routine clinical use, but specialized personnel with sound neurophysiological knowledge and awareness of the strengths and weaknesses of the specific software package used is critical.</div></div>\",\"PeriodicalId\":10671,\"journal\":{\"name\":\"Clinical Neurophysiology\",\"volume\":\"174 \",\"pages\":\"Pages 178-188\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2025-04-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Neurophysiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1388245725005632\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Neurophysiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1388245725005632","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Systematic comparison of Commercial seizure detection Software: Update equals Upgrade?
Objective
To compare two updated commercially available seizure detection software packages (encevis 2.0 and Persyst 14) in a large video-EEG monitoring dataset comprising 80 patients with 6826 h of EEG and 912 seizures.
Methods
We conducted a follow up study of two seizure detection software packages with a significant update since 2021 using different sensitivity settings.
Results
Mean overall seizure count was 11.4 and mean tonic-clonic seizure rate was 0.7 per patient. Detection rates (DR) per patient were 80.7% to 89.1% for encevis 2.0 and 67.3% to 71.1% for Persyst 14. False positive rates (FPR) per day were 12 to 22 for encevis 2.0 and 2 to 4 for Persyst 14.
Conclusions
Encevis 2.0 showed a significantly higher DR than Persyst 14, whereas Persyst 14 showed a significantly lower FPR than encevis 2.0.
Significance
Updated FDA and CE certified seizure detection software showed opposite changes: encevis improved in sensitivity and deteriorated in FPR, while Persyst improved in FPR and deteriorated in sensitivity. In agreement with previous publications, automatic seizure detection software is ready for routine clinical use, but specialized personnel with sound neurophysiological knowledge and awareness of the strengths and weaknesses of the specific software package used is critical.
期刊介绍:
As of January 1999, The journal Electroencephalography and Clinical Neurophysiology, and its two sections Electromyography and Motor Control and Evoked Potentials have amalgamated to become this journal - Clinical Neurophysiology.
Clinical Neurophysiology is the official journal of the International Federation of Clinical Neurophysiology, the Brazilian Society of Clinical Neurophysiology, the Czech Society of Clinical Neurophysiology, the Italian Clinical Neurophysiology Society and the International Society of Intraoperative Neurophysiology.The journal is dedicated to fostering research and disseminating information on all aspects of both normal and abnormal functioning of the nervous system. The key aim of the publication is to disseminate scholarly reports on the pathophysiology underlying diseases of the central and peripheral nervous system of human patients. Clinical trials that use neurophysiological measures to document change are encouraged, as are manuscripts reporting data on integrated neuroimaging of central nervous function including, but not limited to, functional MRI, MEG, EEG, PET and other neuroimaging modalities.