可见光诱导的咔唑-熔融八元重氮杂环化

IF 4.4 2区化学 Q2 CHEMISTRY, APPLIED

Advanced Synthesis & Catalysis Pub Date : 2025-04-22 DOI:10.1002/adsc.202500322

Feng Zhao, Fei Liu, Tongtong Shi, Ting Sun, Lianglong Sun, Si Chen, Xin Wang, Kai Sun

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引用次数: 0

摘要

本文首次在无添加剂、无碱和无外部光敏剂的条件下，描述了一种新的可见光诱导磺化环化反应，以方便地构建具有挑战性的咔唑-融合的八元n杂环。反应条件温和，官能团相容性好，反应可扩展性好，具有进一步工业应用的潜力。通过自由基抑制实验、可见光辐照开关试验、AQE计算和荧光猝灭研究，提出了自由基抑制途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Visible-Light Induced Cyclization to Carbazole-Fused Eight-Membered Diazocan-5-ones

Herein, a novel visible-light-induced sulfonylation cyclization for the facile construction of challenging carbazole-fused eight-membered N-heterocycles has been described for the first time under additive-, base-, and external photosensitizer-free conditions. Mild reaction conditions, good functional group compatibility, and scalability reaction demonstrate the potential for further industrial application. A radical route was proposed based on radical inhibition experiments, visible-light irradiation on-off test, AQE calculation and fluorescence quenching studies.

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来源期刊

Advanced Synthesis & Catalysis 化学-应用化学

CiteScore

9.40

自引率

7.40%

发文量

447

审稿时长

1.8 months

期刊介绍： Advanced Synthesis & Catalysis (ASC) is the leading primary journal in organic, organometallic, and applied chemistry. The high impact of ASC can be attributed to the unique focus of the journal, which publishes exciting new results from academic and industrial labs on efficient, practical, and environmentally friendly organic synthesis. While homogeneous, heterogeneous, organic, and enzyme catalysis are key technologies to achieve green synthesis, significant contributions to the same goal by synthesis design, reaction techniques, flow chemistry, and continuous processing, multiphase catalysis, green solvents, catalyst immobilization, and recycling, separation science, and process development are also featured in ASC. The Aims and Scope can be found in the Notice to Authors or on the first page of the table of contents in every issue.