可见光诱导4czipn催化环丁酮肟酯和苯胺烷基化烯烃

IF 3.3 2区化学 Q1 CHEMISTRY, ORGANIC

Journal of Organic Chemistry Pub Date : 2025-04-22 DOI:10.1021/acs.joc.4c02172

Jiang-Hong Liu, Ze-Yu Tian, Zhen-Ye Wu, Tian-Le Huang, Li Hai, Li Guo, Yong Wu, Zhongzhen Yang

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引用次数: 0

摘要

我们公开了一种有机光氧化催化的三组分氧化自由基-极性交叉策略，用于构建1,2-烷基化产物。以环酮肟衍生物为氰烷基自由基前体，苯胺为亲核试剂。该方法简便，反应产率高，底物范围广。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Visible-Light-Induced 4CzIPN-Catalyzed Alkylamination of Alkenes via Cyclobutanone Oxime Esters and Anilines

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Visible-Light-Induced 4CzIPN-Catalyzed Alkylamination of Alkenes via Cyclobutanone Oxime Esters and Anilines

We disclosed an organophotoredox-catalyzed three-component oxidative radical-polar crossover strategy for constructing 1,2-alkylamination products. Cycloketone oxime derivatives were used as cyanoalkyl radical precursors and anilines were used as the nucleophiles. This facile protocol shows a good reaction yield and broad substrate scope.

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来源期刊

Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.