Mingyi Jiang, Zengcheng Yu, Linhan Yang, Prof. Fei Wang, Prof. Weidi Cao, Prof. Xiaohua Liu, Prof. Xiaoming Feng
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Frontispiz: Reductant-Free Enantioselective Aza-Reformatsky Reaction Enabled by Synergistic Visible Light Photocatalysis and Lewis Acid Catalysis
The visible-light and chiral-Lewis-acid synergistically catalyzed reductant-free asymmetric aza-Reformatsky reaction is described by Xiaoming Feng and co-workers in their Communication (e202500756). Control experiments revealed a direct SET process between excited state imine and α-iodo difluoromethyl carbonyl compound which prevents the use of reductant.