Asli Gorek Dilektasli, Nilüfer Aylin Acet Öztürk, Demet Kerimoğlu, Ayten Odabaş, Mine Tül Yaman, Abdurrahman Dogan, Ezgi Demirdogen, Ozge Aydın Guclu, Funda Coşkun, Ahmet Ursavas, Mehmet Karadağ
{"title":"慢速步态与住院肺科患者的虚弱、日常生活活动和营养状况有关","authors":"Asli Gorek Dilektasli, Nilüfer Aylin Acet Öztürk, Demet Kerimoğlu, Ayten Odabaş, Mine Tül Yaman, Abdurrahman Dogan, Ezgi Demirdogen, Ozge Aydın Guclu, Funda Coşkun, Ahmet Ursavas, Mehmet Karadağ","doi":"10.1007/s40520-025-03040-5","DOIUrl":null,"url":null,"abstract":"<div><h3>Background and aim</h3><p>The 4-meter gait speed (4MGS), a functional performance test, is increasingly used to predict health outcomes. This study investigated 4MGS, nutritional status, frailty, and daily living activities in tertiary care pulmonary diseases ward patients.</p><h3>Methods</h3><p>Patients were assessed for nutritional status, activities of daily living, and frailty using the Mini Nutritional Assessment (MNA) Test, Barthel Questionnaire, and FRAIL scale. Those with 4MGS < 1 m/sec were classified as having slow gait speed.</p><h3>Results</h3><p>80 patients (F/M: 21/59, mean age 58 ± 19) were included. Diagnoses included pneumonia, chronic obstructive pulmonary disease, pleural effusion, and interstitial lung disease. Patients had a 4MGS of 0,74 ± 0,24 m/sn, MNA score of 14.0 [IQR 25–75:11.0–19.8] points, Barthel index of 95 [IQR 25–75:70–100] points, FRAIL scale of 3 [IQR 25–75:1.0–4.0], and a hand-grip strength of 18.8 [IQR 25–75:15.7–25.9] kg. Slow gait speed patients had lower MNA, FRAIL scores, and handgrip strength. Multivariable regression analysis showed that slower gait speed was associated with lower serum protein level (B = 0.013, SE = 0.005, 95% CI: 0.004 to 0.022, <i>p</i> = 0.004), lower hand grip strength (B = -0.002, SE = 0.001, 95% CI: -0.003 to -0.00006, <i>p</i> = 0.041) and malnutrition risk (B = 0.024, SE = 0.007, 95% CI: 0.011 to 0.038, <i>p</i> < 0.001).</p><h3>Discussion and conclusion</h3><p>4MGS correlates with comorbidities, frailty, grip strength, and nutritional status in hospitalized pulmonary patients. Slow gait patients are more malnourished despite similar age, sex, BMI, and comorbidities.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40520-025-03040-5.pdf","citationCount":"0","resultStr":"{\"title\":\"Slow gait speed is associated with frailty, activities of daily living and nutritional status in in-patient pulmonology patients\",\"authors\":\"Asli Gorek Dilektasli, Nilüfer Aylin Acet Öztürk, Demet Kerimoğlu, Ayten Odabaş, Mine Tül Yaman, Abdurrahman Dogan, Ezgi Demirdogen, Ozge Aydın Guclu, Funda Coşkun, Ahmet Ursavas, Mehmet Karadağ\",\"doi\":\"10.1007/s40520-025-03040-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background and aim</h3><p>The 4-meter gait speed (4MGS), a functional performance test, is increasingly used to predict health outcomes. This study investigated 4MGS, nutritional status, frailty, and daily living activities in tertiary care pulmonary diseases ward patients.</p><h3>Methods</h3><p>Patients were assessed for nutritional status, activities of daily living, and frailty using the Mini Nutritional Assessment (MNA) Test, Barthel Questionnaire, and FRAIL scale. Those with 4MGS < 1 m/sec were classified as having slow gait speed.</p><h3>Results</h3><p>80 patients (F/M: 21/59, mean age 58 ± 19) were included. Diagnoses included pneumonia, chronic obstructive pulmonary disease, pleural effusion, and interstitial lung disease. Patients had a 4MGS of 0,74 ± 0,24 m/sn, MNA score of 14.0 [IQR 25–75:11.0–19.8] points, Barthel index of 95 [IQR 25–75:70–100] points, FRAIL scale of 3 [IQR 25–75:1.0–4.0], and a hand-grip strength of 18.8 [IQR 25–75:15.7–25.9] kg. Slow gait speed patients had lower MNA, FRAIL scores, and handgrip strength. Multivariable regression analysis showed that slower gait speed was associated with lower serum protein level (B = 0.013, SE = 0.005, 95% CI: 0.004 to 0.022, <i>p</i> = 0.004), lower hand grip strength (B = -0.002, SE = 0.001, 95% CI: -0.003 to -0.00006, <i>p</i> = 0.041) and malnutrition risk (B = 0.024, SE = 0.007, 95% CI: 0.011 to 0.038, <i>p</i> < 0.001).</p><h3>Discussion and conclusion</h3><p>4MGS correlates with comorbidities, frailty, grip strength, and nutritional status in hospitalized pulmonary patients. 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引用次数: 0
摘要
背景与目的4米步速(4MGS)是一种功能性能测试,越来越多地用于预测健康结果。本研究调查了三级护理肺部疾病病房患者的4MGS、营养状况、虚弱和日常生活活动。方法采用迷你营养评估(MNA)测试、Barthel问卷和虚弱量表对患者的营养状况、日常生活活动和虚弱程度进行评估。4毫克/秒1米/秒的人被归类为步态速度慢。结果共纳入80例患者(F/M: 21/59,平均年龄58±19岁)。诊断包括肺炎、慢性阻塞性肺病、胸腔积液和肺间质性疾病。患者4MGS为0.74±0.24 m/sn, MNA评分为14.0 [IQR 25-75:11.0-19.8]分,Barthel指数为95 [IQR 25-75:70-100]分,体弱量表为3 [IQR 25-75:1.0-4.0],握力为18.8 [IQR 25-75:15.7-25.9] kg。慢速患者的MNA、虚弱评分和握力较低。多变量回归分析显示,步态速度较慢与较低的血清蛋白水平(B = 0.013, SE = 0.005, 95% CI: 0.004 ~ 0.022, p = 0.004)、较低的握力(B = -0.002, SE = 0.001, 95% CI: -0.003 ~ -0.00006, p = 0.041)和营养不良风险(B = 0.024, SE = 0.007, 95% CI: 0.011 ~ 0.038, p < 0.001)相关。讨论与结论4mgs与住院肺部患者的合并症、虚弱、握力和营养状况相关。尽管年龄、性别、BMI和合并症相似,但步态缓慢的患者更容易营养不良。
Slow gait speed is associated with frailty, activities of daily living and nutritional status in in-patient pulmonology patients
Background and aim
The 4-meter gait speed (4MGS), a functional performance test, is increasingly used to predict health outcomes. This study investigated 4MGS, nutritional status, frailty, and daily living activities in tertiary care pulmonary diseases ward patients.
Methods
Patients were assessed for nutritional status, activities of daily living, and frailty using the Mini Nutritional Assessment (MNA) Test, Barthel Questionnaire, and FRAIL scale. Those with 4MGS < 1 m/sec were classified as having slow gait speed.
Results
80 patients (F/M: 21/59, mean age 58 ± 19) were included. Diagnoses included pneumonia, chronic obstructive pulmonary disease, pleural effusion, and interstitial lung disease. Patients had a 4MGS of 0,74 ± 0,24 m/sn, MNA score of 14.0 [IQR 25–75:11.0–19.8] points, Barthel index of 95 [IQR 25–75:70–100] points, FRAIL scale of 3 [IQR 25–75:1.0–4.0], and a hand-grip strength of 18.8 [IQR 25–75:15.7–25.9] kg. Slow gait speed patients had lower MNA, FRAIL scores, and handgrip strength. Multivariable regression analysis showed that slower gait speed was associated with lower serum protein level (B = 0.013, SE = 0.005, 95% CI: 0.004 to 0.022, p = 0.004), lower hand grip strength (B = -0.002, SE = 0.001, 95% CI: -0.003 to -0.00006, p = 0.041) and malnutrition risk (B = 0.024, SE = 0.007, 95% CI: 0.011 to 0.038, p < 0.001).
Discussion and conclusion
4MGS correlates with comorbidities, frailty, grip strength, and nutritional status in hospitalized pulmonary patients. Slow gait patients are more malnourished despite similar age, sex, BMI, and comorbidities.
期刊介绍:
Aging clinical and experimental research offers a multidisciplinary forum on the progressing field of gerontology and geriatrics. The areas covered by the journal include: biogerontology, neurosciences, epidemiology, clinical gerontology and geriatric assessment, social, economical and behavioral gerontology. “Aging clinical and experimental research” appears bimonthly and publishes review articles, original papers and case reports.