Cardiovascular death in patients with acute heart failure in sinus rhythm: Results from the RICA registry

Introduction

Patients with heart failure in sinus rhythm may be at significant risk of major cardiovascular events, including cardiovascular death (CV death).

Objective

To assess CV mortality at a one-year follow up of those patients with heart failure and sinus rhythm, according to LVEF subgroups.

Methods

A prospective and multicentric study was conducted with patients in sinus rhythm included in the National Registry of Heart Failure. Firstly, a demographic, clinical and treatment analysis has been made comparing CV death. Secondly, a multivariate analysis of logistic regression was made including those CV death factors. Lastly, a Kaplan Meyer one year survival was made including LVEF.

Results

Of all 2040 patients included 14.8% presented CV death. The mortality predictors were Barthel index (OR 0.987 (0.982−0.992) [p < 0.001]), LVEF < 40% (OR 1.514 (1.144−2.003) [p 0.003]) and Charlson index (OR 1,069 (1.016−1.124) [p 0.01]).

Conclusion

According to our results CV death has been shown to be higher in those patients with reduced LVEF in sinus rhythm and worst score in Barthel index and Charlson scale.