局部晚期非小细胞肺癌伴气道狭窄，放化疗加杜伐单抗后支架摘除成功：附3例报告

IF 0.7 Q4 RESPIRATORY SYSTEM

Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI:10.1016/j.rmcr.2025.102217

Yuki Takigawa , Ken Sato , Daisuke Minami , Kenichiro Kudo , Shoichiro Matsumoto , Miho Fujiwara , Takeru Ichikawa , Tomoyoshi Inoue , Suzuka Matsuoka , Hiromi Watanabe , Akiko Sato , Hiroyasu Shoda , Nobuhisa Ishikawa , Keiichi Fujiwara , Takuo Shibayama

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引用次数: 0

摘要

在接受放化疗和杜伐单抗治疗后生存期延长的III期非小细胞肺癌（NSCLC）患者中观察到，气道支架改善气道狭窄病例的呼吸条件和东部肿瘤合作组性能状态评分。在此，我们报告了3例III期NSCLC患者在放化疗和杜伐单抗治疗后接受气道支架植入和支架移除。由于分子药物和免疫检查点抑制剂的高反应率，未来移除的支架数量可能会增加。

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Successful stent removal after chemoradiotherapy followed by durvalumab for locally advanced non-small cell lung cancer with airway stenosis: A report of three cases

Airway stents improve respiratory conditions and Eastern Cooperative Oncology Group Performance Status scores in cases of airway stenosis, as observed in patients with stage III non-small cell lung cancer (NSCLC) who experience prolonged survival after undergoing chemoradiotherapy followed by durvalumab treatment. Herein, we report three cases of severe airway stenosis due to stage III NSCLC in patients who underwent airway stenting and subsequent stent removal after chemoradiotherapy and durvalumab administration. The number of stents removed will likely increase in the future due to the high response rates to molecular drugs and immune checkpoint inhibitors.

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