性别包容性研究框架解决临床前研究提案中的性别偏见

IF 15.7 1区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Nature Communications Pub Date : 2025-04-22 DOI:10.1038/s41467-025-58560-5

Natasha A. Karp, Manuel Berdoy, Kelly Gray, Lilian Hunt, Maggy Jennings, Angela Kerton, Matt Leach, Jordi L. Tremoleda, Jon Gledhill, Esther J. Pearl, Nathalie Percie du Sert, Benjamin Phillips, Penny S. Reynolds, Kathy Ryder, S. Clare Stanford, Sara Wells, Lucy Whitfield

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引用次数: 0

摘要

互动式性别包容性研究框架（SIRF）支持对体内和体外研究提案进行评估，以应对临床前研究中的性别偏见风险。该框架提供了一个交通灯分类，显示某项建议在性别包容方面是合适、有风险还是不足。该工具旨在供研究人员、（动物）伦理审查委员会和资助者使用，以便在提案层面对性别包容性进行严格、可重复的评估，从而帮助处理和解决临床前研究中存在的性别偏见。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The Sex Inclusive Research Framework to address sex bias in preclinical research proposals

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The Sex Inclusive Research Framework to address sex bias in preclinical research proposals

An interactive Sex Inclusive Research Framework (SIRF) supports the evaluation of in vivo and ex vivo research proposals to address the risk of sex bias in preclinical research. The framework delivers a traffic light classification, indicating whether a proposal is appropriate, risky, or insufficient with regard to sex inclusion. This tool is designed for use by researchers, (animal) ethical review boards, and funders to generate a rigorous and reproducible assessment of sex inclusion at the proposal level, thus helping address and resolve the embedded sex bias in preclinical research.

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来源期刊

Nature Communications Biological Science Disciplines-

CiteScore

24.90

自引率

2.40%

发文量

6928

审稿时长

3.7 months

期刊介绍： Nature Communications, an open-access journal, publishes high-quality research spanning all areas of the natural sciences. Papers featured in the journal showcase significant advances relevant to specialists in each respective field. With a 2-year impact factor of 16.6 (2022) and a median time of 8 days from submission to the first editorial decision, Nature Communications is committed to rapid dissemination of research findings. As a multidisciplinary journal, it welcomes contributions from biological, health, physical, chemical, Earth, social, mathematical, applied, and engineering sciences, aiming to highlight important breakthroughs within each domain.