胶原基质和结缔组织移植对种植体周围软组织增重的3d分析:一项随机对照试验

IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Igor Ashurko, Svetlana Tarasenko, Mary Magdalyanova, Maxim Balyasin, Anna Galyas, Sabina Kazumyan, Nadiya Safi, Alexey Unkovskiy
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引用次数: 0

摘要

目的 比较结缔组织移植(SCTG)和胶原基质(VXCM)在单个种植体周围颊部软组织增量方面的疗效。 方法 该研究设计为随机对照临床试验。该试验已在 ClinicalTrial.gov 上注册,标识符为 NCT05870774,可通过以下链接访问:https://clinicaltrials.gov/study/NCT05870774?term=NCT05870774&rank=1。该临床试验在参与者招募和随机化之前并未注册。有单齿隙和水平软组织厚度不足的患者被纳入研究。患者被随机分配到对照组(SCTG)或试验组(VXCM:Geistlich Fibro-Gide,Geistlich Pharma AG,瑞士 Wolhusen),以增加颊软组织厚度。主要结果是术后 3 个月的软组织增厚。次要结果包括术后 6 个月的软组织增厚、粉色美学评分 (PES) 和患者报告结果测量 (PROM)。 结果 患者招募于 2021 年 10 月 28 日开始,2022 年 12 月 25 日结束。32名患者入组并接受了干预。每组 16 名患者。术后三个月,VXCM 组颊面部位的软组织增厚为 1.77 ± 0.61 mm,SCTG 组为 1.26 ± 0.41 mm(p = 0.0003)。术后六个月,VXCM 组的软组织增厚为 1.11 ± 0.44 毫米,SCTG 组为 1.43 ± 0.81 毫米(p = 0.0459)。包括痛觉在内的 PROM 显示,VXCM 组更受青睐。SCTG 在 PES 方面的结果更佳。 结论 就临床效果而言,SCTG 仍是增加软组织厚度的黄金标准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

3D-Analysis of Peri-Implant Soft Tissue Gain With Collagen Matrix and Connective Tissue Graft: A Randomized Control Trial

3D-Analysis of Peri-Implant Soft Tissue Gain With Collagen Matrix and Connective Tissue Graft: A Randomized Control Trial

Objectives

To compare the efficacy of the connective tissue graft (SCTG) and the collagen matrix (VXCM) in terms of soft tissue gain at the buccal site around a single implant.

Methods

The study was designed as a randomized, controlled clinical trial. This trial was registered in ClinicalTrial.gov with the identifier NCT05870774 and is accessible under the following link: https://clinicaltrials.gov/study/NCT05870774?term=NCT05870774&rank=1. This clinical trial was not registered prior to participant recruitment and randomization. Patients with a single tooth gap and horizontal soft tissue thickness deficiency were enrolled in the study. Sites were randomly allocated to the control (SCTG) or test group (VXCM: Geistlich Fibro-Gide, Geistlich Pharma AG, Wolhusen, Switzerland) to augment buccal soft tissue thickness. The primary outcome was soft tissue gain 3 months post-op. Secondary outcomes included soft tissue gain 6 months post-op, the pink aesthetic score (PES), and patient-reported outcome measures (PROMs).

Results

Patients' recruitment started on 28 October 2021 and ended on 25 December 2022. Thirty-two patients were enrolled and subjected to intervention. Sixteen patients were included per group. Three months post-op, soft tissue gain at the buccal site was 1.77 ± 0.61 mm in the VXCM group and 1.26 ± 0.41 mm in the SCTG group (p = 0.0003). Six months post-op, soft tissue gain was 1.11 ± 0.44 mm in the VXCM group and 1.43 ± 0.81 mm in the SCTG group (p = 0.0459). PROMs, including pain perception, favored the VXCM group. SCTG demonstrated favored results in PES.

Conclusion

SCTG remains the gold standard for increasing soft tissue thickness in terms of the clinical result.

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来源期刊
CiteScore
6.00
自引率
13.90%
发文量
103
审稿时长
4-8 weeks
期刊介绍: The goal of Clinical Implant Dentistry and Related Research is to advance the scientific and technical aspects relating to dental implants and related scientific subjects. Dissemination of new and evolving information related to dental implants and the related science is the primary goal of our journal. The range of topics covered by the journals will include but be not limited to: New scientific developments relating to bone Implant surfaces and their relationship to the surrounding tissues Computer aided implant designs Computer aided prosthetic designs Immediate implant loading Immediate implant placement Materials relating to bone induction and conduction New surgical methods relating to implant placement New materials and methods relating to implant restorations Methods for determining implant stability A primary focus of the journal is publication of evidenced based articles evaluating to new dental implants, techniques and multicenter studies evaluating these treatments. In addition basic science research relating to wound healing and osseointegration will be an important focus for the journal.
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