Igor Ashurko, Svetlana Tarasenko, Mary Magdalyanova, Maxim Balyasin, Anna Galyas, Sabina Kazumyan, Nadiya Safi, Alexey Unkovskiy
{"title":"胶原基质和结缔组织移植对种植体周围软组织增重的3d分析:一项随机对照试验","authors":"Igor Ashurko, Svetlana Tarasenko, Mary Magdalyanova, Maxim Balyasin, Anna Galyas, Sabina Kazumyan, Nadiya Safi, Alexey Unkovskiy","doi":"10.1111/cid.70043","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objectives</h3>\n \n <p>To compare the efficacy of the connective tissue graft (SCTG) and the collagen matrix (VXCM) in terms of soft tissue gain at the buccal site around a single implant.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>The study was designed as a randomized, controlled clinical trial. This trial was registered in ClinicalTrial.gov with the identifier NCT05870774 and is accessible under the following link: https://clinicaltrials.gov/study/NCT05870774?term=NCT05870774&rank=1. This clinical trial was not registered prior to participant recruitment and randomization. Patients with a single tooth gap and horizontal soft tissue thickness deficiency were enrolled in the study. Sites were randomly allocated to the control (SCTG) or test group (VXCM: Geistlich Fibro-Gide, Geistlich Pharma AG, Wolhusen, Switzerland) to augment buccal soft tissue thickness. The primary outcome was soft tissue gain 3 months post-op. Secondary outcomes included soft tissue gain 6 months post-op, the pink aesthetic score (PES), and patient-reported outcome measures (PROMs).</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Patients' recruitment started on 28 October 2021 and ended on 25 December 2022. Thirty-two patients were enrolled and subjected to intervention. Sixteen patients were included per group. Three months post-op, soft tissue gain at the buccal site was 1.77 ± 0.61 mm in the VXCM group and 1.26 ± 0.41 mm in the SCTG group (<i>p</i> = 0.0003). Six months post-op, soft tissue gain was 1.11 ± 0.44 mm in the VXCM group and 1.43 ± 0.81 mm in the SCTG group (<i>p</i> = 0.0459). PROMs, including pain perception, favored the VXCM group. SCTG demonstrated favored results in PES.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>SCTG remains the gold standard for increasing soft tissue thickness in terms of the clinical result.</p>\n </section>\n </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 2","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.70043","citationCount":"0","resultStr":"{\"title\":\"3D-Analysis of Peri-Implant Soft Tissue Gain With Collagen Matrix and Connective Tissue Graft: A Randomized Control Trial\",\"authors\":\"Igor Ashurko, Svetlana Tarasenko, Mary Magdalyanova, Maxim Balyasin, Anna Galyas, Sabina Kazumyan, Nadiya Safi, Alexey Unkovskiy\",\"doi\":\"10.1111/cid.70043\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>To compare the efficacy of the connective tissue graft (SCTG) and the collagen matrix (VXCM) in terms of soft tissue gain at the buccal site around a single implant.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>The study was designed as a randomized, controlled clinical trial. This trial was registered in ClinicalTrial.gov with the identifier NCT05870774 and is accessible under the following link: https://clinicaltrials.gov/study/NCT05870774?term=NCT05870774&rank=1. This clinical trial was not registered prior to participant recruitment and randomization. Patients with a single tooth gap and horizontal soft tissue thickness deficiency were enrolled in the study. Sites were randomly allocated to the control (SCTG) or test group (VXCM: Geistlich Fibro-Gide, Geistlich Pharma AG, Wolhusen, Switzerland) to augment buccal soft tissue thickness. The primary outcome was soft tissue gain 3 months post-op. Secondary outcomes included soft tissue gain 6 months post-op, the pink aesthetic score (PES), and patient-reported outcome measures (PROMs).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Patients' recruitment started on 28 October 2021 and ended on 25 December 2022. Thirty-two patients were enrolled and subjected to intervention. Sixteen patients were included per group. Three months post-op, soft tissue gain at the buccal site was 1.77 ± 0.61 mm in the VXCM group and 1.26 ± 0.41 mm in the SCTG group (<i>p</i> = 0.0003). Six months post-op, soft tissue gain was 1.11 ± 0.44 mm in the VXCM group and 1.43 ± 0.81 mm in the SCTG group (<i>p</i> = 0.0459). PROMs, including pain perception, favored the VXCM group. 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3D-Analysis of Peri-Implant Soft Tissue Gain With Collagen Matrix and Connective Tissue Graft: A Randomized Control Trial
Objectives
To compare the efficacy of the connective tissue graft (SCTG) and the collagen matrix (VXCM) in terms of soft tissue gain at the buccal site around a single implant.
Methods
The study was designed as a randomized, controlled clinical trial. This trial was registered in ClinicalTrial.gov with the identifier NCT05870774 and is accessible under the following link: https://clinicaltrials.gov/study/NCT05870774?term=NCT05870774&rank=1. This clinical trial was not registered prior to participant recruitment and randomization. Patients with a single tooth gap and horizontal soft tissue thickness deficiency were enrolled in the study. Sites were randomly allocated to the control (SCTG) or test group (VXCM: Geistlich Fibro-Gide, Geistlich Pharma AG, Wolhusen, Switzerland) to augment buccal soft tissue thickness. The primary outcome was soft tissue gain 3 months post-op. Secondary outcomes included soft tissue gain 6 months post-op, the pink aesthetic score (PES), and patient-reported outcome measures (PROMs).
Results
Patients' recruitment started on 28 October 2021 and ended on 25 December 2022. Thirty-two patients were enrolled and subjected to intervention. Sixteen patients were included per group. Three months post-op, soft tissue gain at the buccal site was 1.77 ± 0.61 mm in the VXCM group and 1.26 ± 0.41 mm in the SCTG group (p = 0.0003). Six months post-op, soft tissue gain was 1.11 ± 0.44 mm in the VXCM group and 1.43 ± 0.81 mm in the SCTG group (p = 0.0459). PROMs, including pain perception, favored the VXCM group. SCTG demonstrated favored results in PES.
Conclusion
SCTG remains the gold standard for increasing soft tissue thickness in terms of the clinical result.
期刊介绍:
The goal of Clinical Implant Dentistry and Related Research is to advance the scientific and technical aspects relating to dental implants and related scientific subjects. Dissemination of new and evolving information related to dental implants and the related science is the primary goal of our journal.
The range of topics covered by the journals will include but be not limited to:
New scientific developments relating to bone
Implant surfaces and their relationship to the surrounding tissues
Computer aided implant designs
Computer aided prosthetic designs
Immediate implant loading
Immediate implant placement
Materials relating to bone induction and conduction
New surgical methods relating to implant placement
New materials and methods relating to implant restorations
Methods for determining implant stability
A primary focus of the journal is publication of evidenced based articles evaluating to new dental implants, techniques and multicenter studies evaluating these treatments. In addition basic science research relating to wound healing and osseointegration will be an important focus for the journal.