在曲霉病和毛霉病的基础研究方面处于领先地位

IF 2.9 3区生物学 Q2 MYCOLOGY

Fungal biology Pub Date : 2025-04-08 DOI:10.1016/j.funbio.2025.101574

Argha Sarkar , Drauzio E.N. Rangel , Nir Osherov

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引用次数: 0

摘要

这篇社论概述了2022年至2024年间发表的有关曲霉菌病和粘孢子菌病基础研究的重要成果。曲霉菌病的基础研究在基因组学领域取得了重大进展，对数百个分离菌株进行了廉价的全基因组测序。这加深了我们对烟曲霉菌群结构、基因多样性和唑类抗真菌耐药性进化的了解。在粘孢子虫病的基础研究中，我们对小孢子根瘤菌与内生细菌之间的相互作用有了有趣的了解，这种相互作用保护小孢子根瘤菌免受掠夺性土壤变形虫的侵害，并增强了其在感染模型中的毒力。

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Leading developments in basic research on aspergillosis and mucormycosis

This editorial presents an overview of notable contributions in basic research on aspergillosis and mucormycosis published between 2022 and 2024. Basic research in aspergillosis saw major advances in the field of genomics brought about by inexpensive whole-genome sequencing of hundreds of isolates. This has deepened our understanding of Aspergillus fumigatus population structure, gene diversity, and the evolution of azole antifungal resistance. Basic research in mucormycosis saw interesting developments in our understanding of the interactions between Rhizopus microsporus and endosymbiotic bacteria that protect it against predatory soil amoeba and increase its virulence in models of infection.

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来源期刊

Fungal biology MYCOLOGY-

CiteScore

5.80

自引率

4.00%

发文量

审稿时长

49 days

期刊介绍： Fungal Biology publishes original contributions in all fields of basic and applied research involving fungi and fungus-like organisms (including oomycetes and slime moulds). Areas of investigation include biodeterioration, biotechnology, cell and developmental biology, ecology, evolution, genetics, geomycology, medical mycology, mutualistic interactions (including lichens and mycorrhizas), physiology, plant pathology, secondary metabolites, and taxonomy and systematics. Submissions on experimental methods are also welcomed. Priority is given to contributions likely to be of interest to a wide international audience.