一种新型可调节大小的低温球囊对31毫米大小的正中病变大小的前瞻性评价:BETTER-FIT研究的结果

IF 2.5 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Nick van Boven MD, PhD , Rohit Bhagwandien MD , Sip A. Wijchers MD , Mark Hoogendijk MD, PhD , Bakhtawar Khan Mahmoodi MD, PhD , Sing-Chien Yap MD, PhD
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引用次数: 0

摘要

一种新型的可调节大小的冷冻球囊可以提供28或31毫米大小的冷冻治疗。然而,关于31毫米球囊大小的窦室病变大小的资料很少。目的评价31 mm球囊大小冷冻消融对心窦损伤的影响。方法本前瞻性单中心研究纳入首次肺静脉隔离(PVI)治疗的阵发性心房颤动患者。所有肺静脉(pv)首先用31毫米球囊大小消融。28毫米的气球尺寸仅用于紧急救援。消融前后行左心房超高清定位,评估心房病变区域。次要结局指标是程序疗效,包括球囊阻塞等级。结果20例80例PVI患者均实现完全PVI(平均年龄59.7±10.7岁,男性占75%)。超过三分之一的后壁消融(35.4%±13.8%),分离表面积为68.7%±8.5%。外侧、中隔周围正中病变面积分别为12.1±2.0 cm2和19.1±4.7 cm2。一名患者表现出鼻窦顶部病变的无意重叠。与28毫米球囊大小相比,31毫米球囊大小的右上PV有更低球囊完全闭塞的趋势(75%和90%,P = .08)。结论采用31mm大小的新型可调节冷冻球囊进行冷冻消融可造成较大的心窦病变。在小心房,当在两个上心室使用31毫米球囊时,有可能在屋顶留下一个小的未消融的走廊,这可能是致心律失常的原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prospective evaluation of antral lesion size of the 31-mm size of a novel size-adjustable cryoballoon: Results of the BETTER-FIT study

Background

A novel size-adjustable cryoballoon can deliver cryotherapy with a 28- or 31-mm balloon size. However, data on antral lesion size with the 31-mm balloon size are scarce.

Objective

The purpose of this study was to evaluate the antral lesion size of cryoablation with the 31-mm balloon size.

Methods

This prospective single-center study included patients with paroxysmal atrial fibrillation undergoing first-time pulmonary vein isolation (PVI). All pulmonary veins (PVs) were first ablated with the 31-mm balloon size. The 28-mm balloon size was only used as bailout. Pre- and postablation left atrial ultrahigh-definition mapping was performed to assess the antral lesion area. Secondary outcome measures were procedural efficacy including balloon occlusion grade.

Results

Complete PVI was achieved in all 80 PVs in 20 patients (mean age 59.7 ± 10.7 years, 75% male). More than one-third of the posterior wall was ablated (35.4% ± 13.8%), and the isolated surface area was 68.7% ± 8.5%. Lateral and septal circumferential antral lesion areas were 12.1 ± 2.0 cm2 and 19.1 ± 4.7 cm2, respectively. One patient demonstrated inadvertent overlap of the antral lesions on the roof. There was a trend toward lower complete balloon occlusion in the right superior PV with the 31-mm balloon size in comparison to the 28-mm size (75% and 90%, P = .08).

Conclusion

Cryoablation with the 31-mm size of a novel size-adjustable cryoballoon results in a large antral lesion. In small atria there is the potential for leaving a small nonablated corridor on the roof when using the 31-mm balloon in both superior PVs, which may be proarrhythmogenic.
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来源期刊
Heart Rhythm O2
Heart Rhythm O2 Cardiology and Cardiovascular Medicine
CiteScore
3.30
自引率
0.00%
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审稿时长
52 days
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