United effect of nonthermal plasma driven O3 water and phenolic compounds for bacterial biofilm quorum sensing reduction under the O3 processed nitro-hydroxylation and norfloxacin remediation via oxidation

The united effect of nonthermal plasma driven $O_3$ water and phenolic compounds were strongly responsible for bacterial biofilm quorum sensing (QS) inhibition through the $O_3$ species processed nitro-hydroxylation. The $O_3$ species were strongly interacted with phenolic compounds to performed the hydroxylation and nitration in the water via oxidation and reduction through the aromatic and aliphatic benzene ring dissociation and association of $e^{-}$ exchange process. The $O_3$ with phenolic compounds were strongly responsible for S. mutans and candida albicans biofilm growth inhibition via oxidative process than only $O_3$ water and only phenolic compounds. The united effect obligated to be inactivated the S. mutans and candida albicans consisted proteins and peptides molecules, and quorum sensing molecules. Furthermore, the $O_3$ species and phenolic compounds processed oxygen, hydrogen evaluation reactions (OER and HER), and CO₂ conversion potential charges (∆G) were evaluated for oxidative study. Meanwhile, the plasma produced free radicals, such as $O_3$, $H_2{O}_2$, and NO_x species were strongly responsible for removal of norfloxacin (NOF), whose removal % 96.11 %. In this research, the suggested plasma driven water and phenolic compounds were responsible for the bacterial and fungal biofilm QS inhibition through the advanced united oxidative process, and along with micropollutants removal.