尼罗罗非鱼对东方Francisella orientalis的抗性遗传选择显示出显著的选择响应

IF 3.9 1区农林科学 Q1 FISHERIES

Aquaculture Pub Date : 2025-04-15 DOI:10.1016/j.aquaculture.2025.742584

Baltasar F. Garcia , Jairo A. Restrepo-Arango , Marcelo S. Silva Filho , Elielma L. Sousa , John F.G. Agudelo , Vito A. Mastrochirico-Filho , Shisley C.S. Manso , Carolina S. Pereira , Danielle C. Dias , Antonio F.G. Leonardo , Fernando S. Fonseca , Leonardo Tachibana , Maria J.T. Ranzani-Paiva , Fabiana Pilarski , Diogo T. Hashimoto

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引用次数: 0

摘要

尼罗罗非鱼（Oreochromis niloticus）是主要的水产养殖品种之一，但其生产经常受到新出现的疾病的挑战，如由东方Francisella orientalis引起的franciselllosis。选择抗病育种为防止农业设施中的疾病暴发提供了一种可持续的替代方法。本研究旨在估计尼罗罗非鱼的遗传参数，并评价其对东方飞虱抗性的选择反应。我们进行了两代（G0和G1）的连续攻毒试验，利用包括二值生存（BS）和死亡时间（TD）在内的家系信息来评估抗性性状的遗传力（h2）。另外，G1区6个家系作为对照，由估计育种值（EBV）最低的育种家系组成。利用BS性状估计对选择的实现响应（ΔGR）。在第二次挑战中，利用TD性状的遗传参数估计了对选择的预期响应（ΔGE）。G1期平均TD值低于G1期，分别为56.59±17.27 h和73.70±27.68 h。G0、G1和G0 + G1的h2预测值分别为0.399±0.07、0.282±0.08和0.593±0.07，BS的h2预测值分别为0.454±0.07、0.266±0.06和0.478±0.06。在家族水平上，G1组的ΔGR为- 0.144，G1组为- 0.0638，G1组为0.0122，表明抗性选择具有正向作用。ΔGE显示，根据选择强度的不同，下一代TD的潜在遗传增益为33 ~ 109 h。该研究发现，尼罗罗非鱼对东方飞虱的抗性具有显著的加性遗传成分，选择性育种可以有效地提高抗病性，具有跨代快速遗传增益的潜力。

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Genetic selection for resistance to Francisella orientalis shows significant selection response in Nile tilapia

Nile tilapia (Oreochromis niloticus) is one of the major aquaculture species, but its production is often challenged by emerging diseases, as francisellosis caused by Francisella orientalis. Selective breeding for disease resistance offers a sustainable alternative to prevent outbreaks in farming facilities. This study aimed to estimate the genetic parameters and evaluate the response to selection for resistance to F. orientalis in Nile tilapia. We conducted two sequential challenge tests across two generations (G0 and G1) to assess the heritability (

h^{2}

) of resistance traits using pedigree information, including binary survival (BS) and time to death (TD). Additionally, six families in G1 were designated as controls, consisting of breeders with the lowest estimated breeding values (EBV). The realized response to selection (ΔG_R) was estimated using the BS trait. The expected response to selection (ΔG_E) was also estimated using the genetic parameters of the TD trait in the second challenge. Average TD results were lower in G1 than G0, 56.59 ± 17.27 and 73.70 ± 27.68 h, respectively. The

h^{2}

estimates for G0, G1 and G0 + G1 were 0.399 ± 0.07, 0.282 ± 0.08 and 0.593 ± 0.07 for TD, and 0.454 ± 0.07, 0.266 ± 0.06 and 0.478 ± 0.06 for BS. The ΔG_R at the family level were − 0.144 for G1 control, −0.0638 for G0, and 0.0122 for G1 resistance, indicating a positive effect of selection for resistance. The ΔG_E showed potential genetic gains of 33 to 109 h in TD for the next generation depending on the selection intensity. The study found that resistance to F. orientalis in Nile tilapia has a significant additive genetic component and selective breeding can effectively improve disease resistance, with the potential for rapid genetic gains across generations.

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来源期刊

Aquaculture 农林科学-海洋与淡水生物学

CiteScore

8.60

自引率

17.80%

发文量

1246

审稿时长

56 days

期刊介绍： Aquaculture is an international journal for the exploration, improvement and management of all freshwater and marine food resources. It publishes novel and innovative research of world-wide interest on farming of aquatic organisms, which includes finfish, mollusks, crustaceans and aquatic plants for human consumption. Research on ornamentals is not a focus of the Journal. Aquaculture only publishes papers with a clear relevance to improving aquaculture practices or a potential application.