{"title":"一名免疫力低下患者因皮下副蝶形花引起的不寻常皮下真菌病","authors":"Pooja Naharia , Santosh Karade , Rajiv Kumar , Anita Sharma","doi":"10.1016/j.diagmicrobio.2025.116836","DOIUrl":null,"url":null,"abstract":"<div><div>Solid Organ transplant recipients are at risk of opportunistic infections due to immunosuppressed state, prolonged hospital stay and exposure to multiple antibiotics. Subcutaneous mycoses are heterogenous group of fungal infections affecting dermis and subcutaneous tissue due to penetrating injury. Subcutaneous mycosis in immunocompromised individual causes significant morbidity in the form of chronic discharging sinuses and systemic spread. <em>Parathyridaria percutanea</em> is an emerging cause of subcutaneous mycosis in transplant patients and is difficult to identify phenotypically. It is relatively novel pathogen and only few cases are reported in Indian population. Here we present a case of subcutaneous mycosis who presented with multiple discharging sinuses over left foot. Timely identification of implicating pathogen and initiation of targeted anti-fungal therapy plays important role in decreasing hospital stay and overall financial burden to patient. Present case also highlights importance of genotypic methods in diagnosing emerging fungal infection in immunocompromised individuals, when phenotypic identification fails.</div></div>","PeriodicalId":11329,"journal":{"name":"Diagnostic microbiology and infectious disease","volume":"112 4","pages":"Article 116836"},"PeriodicalIF":2.1000,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An unusual subcutaneous mycosis due to Parathyridaria percutanea in an immunocompromised individual\",\"authors\":\"Pooja Naharia , Santosh Karade , Rajiv Kumar , Anita Sharma\",\"doi\":\"10.1016/j.diagmicrobio.2025.116836\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Solid Organ transplant recipients are at risk of opportunistic infections due to immunosuppressed state, prolonged hospital stay and exposure to multiple antibiotics. Subcutaneous mycoses are heterogenous group of fungal infections affecting dermis and subcutaneous tissue due to penetrating injury. Subcutaneous mycosis in immunocompromised individual causes significant morbidity in the form of chronic discharging sinuses and systemic spread. <em>Parathyridaria percutanea</em> is an emerging cause of subcutaneous mycosis in transplant patients and is difficult to identify phenotypically. It is relatively novel pathogen and only few cases are reported in Indian population. Here we present a case of subcutaneous mycosis who presented with multiple discharging sinuses over left foot. Timely identification of implicating pathogen and initiation of targeted anti-fungal therapy plays important role in decreasing hospital stay and overall financial burden to patient. Present case also highlights importance of genotypic methods in diagnosing emerging fungal infection in immunocompromised individuals, when phenotypic identification fails.</div></div>\",\"PeriodicalId\":11329,\"journal\":{\"name\":\"Diagnostic microbiology and infectious disease\",\"volume\":\"112 4\",\"pages\":\"Article 116836\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-04-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diagnostic microbiology and infectious disease\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0732889325001592\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic microbiology and infectious disease","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0732889325001592","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
An unusual subcutaneous mycosis due to Parathyridaria percutanea in an immunocompromised individual
Solid Organ transplant recipients are at risk of opportunistic infections due to immunosuppressed state, prolonged hospital stay and exposure to multiple antibiotics. Subcutaneous mycoses are heterogenous group of fungal infections affecting dermis and subcutaneous tissue due to penetrating injury. Subcutaneous mycosis in immunocompromised individual causes significant morbidity in the form of chronic discharging sinuses and systemic spread. Parathyridaria percutanea is an emerging cause of subcutaneous mycosis in transplant patients and is difficult to identify phenotypically. It is relatively novel pathogen and only few cases are reported in Indian population. Here we present a case of subcutaneous mycosis who presented with multiple discharging sinuses over left foot. Timely identification of implicating pathogen and initiation of targeted anti-fungal therapy plays important role in decreasing hospital stay and overall financial burden to patient. Present case also highlights importance of genotypic methods in diagnosing emerging fungal infection in immunocompromised individuals, when phenotypic identification fails.
期刊介绍:
Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.