美国抑郁症导致自杀：1999年至2022年CDC WONDER的回顾性分析

IF 3.7 2区医学 Q1 PSYCHIATRY

Journal of psychiatric research Pub Date : 2025-04-11 DOI:10.1016/j.jpsychires.2025.04.016

Abdullah , Bazil Azeem , Momina Riaz Siddiqui , Samiullah Shaikh , Ammad Sattar , Humza Saeed

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引用次数: 0

摘要

抑郁症在美国是一种普遍的精神健康状况，自杀一直是抑郁症患者死亡的主要原因。本研究旨在分析1999年至2022年美国抑郁症患者的自杀死亡率趋势。方法从CDC WONDER数据库中提取数据，分别使用ICD-10-CM代码（F32、F33、F41.2、F92.0）和ICD-10-CM代码（U03、X60-X84、Y87.0）识别抑郁相关死亡和自杀相关死亡。计算每100万人的年龄调整死亡率（AAMRs）和年变化百分比（APCs），并按年份、性别、年龄组、种族/民族、地区和城市化状况进行分层。结果共分析自杀和抑郁症死亡57103例。从1999年到2022年，AAMR从1999年到2015年显著增加(APC: 2.05；95% ci: 1.65-2.74；p & lt;0.0001)，其次是2015 - 2022年的稳定趋势(APC: 0.81；95% CI: 3.67 ~ 0.36；p = 0.14)。男性的aamr（10）始终高于女性（3.9），在50-59岁年龄组中观察到的比率最高（11.2）。非西班牙裔（NH）白人个体的AAMRs最高（9.9），其次是NH美洲印第安人/阿拉斯加原住民（3.7），NH黑人个体的AAMRs最低（1.9）。农村地区的发病率（12.5）明显高于城市地区（5.4），其中美国西部地区的增幅最大[年均百分比变化（AAPC）： 2.44；95% CI: 1.76 ~ 3.49]。结论：本研究揭示了自杀和抑郁相关死亡率的人口统计学和地理差异。解决高风险群体的不成比例负担可以指导未来的预防战略，以减缓上升的趋势（中央插图）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Depression leading to suicide in United States: A retrospective analysis of CDC WONDER from 1999 to 2022

查看原文本刊更多论文

Depression leading to suicide in United States: A retrospective analysis of CDC WONDER from 1999 to 2022

Background

Depressive disorder is a prevalent mental health condition in the United States, where suicide has been a leading cause of death among depressive patients. This study aimed to analyze suicide mortality trends in depressive disorder patients in the U.S. from 1999 to 2022.

Methods

Data were extracted from the CDC WONDER database, identifying depression-related and suicide-related deaths using ICD-10-CM codes (F32, F33, F41.2, F92.0) and ICD-10-CM codes (U03, X60-X84, Y87.0) respectively. Age-adjusted mortality rates (AAMRs) per 1,000,000 and annual percent changes (APCs) were calculated and stratified by year, gender, age-group, race/ethnicity, region, and urbanization status.

Results

A total of 57,103 deaths due to suicide and depressive disorder were analyzed. From 1999 to 2022, the AAMR significantly increased from 1999 to 2015 (APC: 2.05; 95 % CI: 1.65–2.74; p < 0.0001), followed by a stable trend from 2015 to 2022 (APC: 0.81; 95 % CI: 3.67 to 0.36; p = 0.14). Men consistently exhibited higher AAMRs (10) than women (3.9), with particularly highest rates observed in the 50–59 age group (11.2). Non-Hispanic (NH) White individuals had the highest AAMRs (9.9), followed by NH American Indian/Alaska Native populations (3.7), and NH Black individuals exhibiting the lowest rates (1.9). Rural areas showed significantly higher rates (12.5) compared to urban areas (5.4), with the Western U.S. region experiencing the steepest increases [Average Annual Percent Change (AAPC): 2.44; 95 % CI: 1.76 to 3.49].

Conclusion

This study reveals critical demographic and geographic disparities in suicide and depression-related mortality. Addressing the disproportionate burden on high-risk groups can guide future preventive strategies to mitigate the rising trends (Central Illustration).

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来源期刊

Journal of psychiatric research 医学-精神病学

CiteScore

7.30

自引率

2.10%

发文量

622

审稿时长

130 days

期刊介绍： Founded in 1961 to report on the latest work in psychiatry and cognate disciplines, the Journal of Psychiatric Research is dedicated to innovative and timely studies of four important areas of research: (1) clinical studies of all disciplines relating to psychiatric illness, as well as normal human behaviour, including biochemical, physiological, genetic, environmental, social, psychological and epidemiological factors; (2) basic studies pertaining to psychiatry in such fields as neuropsychopharmacology, neuroendocrinology, electrophysiology, genetics, experimental psychology and epidemiology; (3) the growing application of clinical laboratory techniques in psychiatry, including imagery and spectroscopy of the brain, molecular biology and computer sciences;