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新型靶向FKBP12的PROTAC：增强多发性骨髓瘤骨形态发生蛋白活性和细胞凋亡的潜力

IF 8.2 1区 医学 Q1 HEMATOLOGY
Haematologica Pub Date : 2025-04-17 DOI:10.3324/haematol.2024.287047
Ingrid Quist-Lokken,Mira Tilseth,Clara Andersson-Rusch,Md Abu Hanif,Michael Walz,Johanna Fredrikke Nordstrand Moen,Megan Anne Vik,Tobias Schmidt Slordahl,Anders Sundan,Felix Hausch,Toril Holien
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Novel PROTAC to target FKBP12: the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myeloma.
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来源期刊
Haematologica
Haematologica 医学-血液学
CiteScore
14.10
自引率
2.00%
发文量
349
审稿时长
3-6 weeks
期刊介绍： Haematologica is a journal that publishes articles within the broad field of hematology. It reports on novel findings in basic, clinical, and translational research. Scope: The scope of the journal includes reporting novel research results that: Have a significant impact on understanding normal hematology or the development of hematological diseases. Are likely to bring important changes to the diagnosis or treatment of hematological diseases.
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