还原性胺化开/关氧化环合成氮杂环的研究

IF 2.8 4区化学 Q1 CHEMISTRY, ORGANIC

Asian Journal of Organic Chemistry Pub Date : 2025-04-01 DOI:10.1002/ajoc.202400818

Melinda Nonn , Róbert Berkecz , Santos Fustero , Ágnes Lackfi , Gábor Hornyánszky , Loránd Kiss

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引用次数: 0

摘要

以各种环烯烃衍生物为原料，通过还原胺化氧化开环/闭环，通过扩环法制备了功能化饱和氮杂环。对变形的结果、环应变的影响和立体控制进行了研究。合成的结构中含有芳基或氟元素的氨基酸衍生物可能是折叠体化学的相关组成部分。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Studies on the Synthesis of Some Functionalized Azaheterocycles through Oxidative Ring Opening/Ring Closing by Reductive Amination

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Studies on the Synthesis of Some Functionalized Azaheterocycles through Oxidative Ring Opening/Ring Closing by Reductive Amination

Selected functionalized saturated azaheterocycles have been prepared by ring expansion from various cycloalkene derivatives involving oxidative ring opening/ring closing by reductive amination. Studies have been conducted regarding the outcome of the transformations, the effect of the ring strain, and stereocontrol. The synthesized amino acid derivatives possessing either an aryl or fluorine element in their structure might be relevant building blocks for foldamer chemistry.

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来源期刊

Asian Journal of Organic Chemistry CHEMISTRY, ORGANIC-

CiteScore

4.70

自引率

3.70%

发文量

372

期刊介绍： Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC) The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.