Daniel Schwaiger, Armin Krösbacher, Christine Eckhardt, Lukas Schausberger, Michael Baubin, Sasa Rajsic
{"title":"院外心脏骤停:10年生存率和神经预后分析","authors":"Daniel Schwaiger, Armin Krösbacher, Christine Eckhardt, Lukas Schausberger, Michael Baubin, Sasa Rajsic","doi":"10.1016/j.hrtlng.2025.04.003","DOIUrl":null,"url":null,"abstract":"<div><div><strong>Background</strong> Out-of-hospital cardiac arrest (OHCA) is a major public health issue with low survival rates.</div><div><strong>Objective</strong> Identification of predictors for survival and good neurological outcomes following OHCA.</div><div><strong>Methods</strong> This retrospective study included all OHCA patients between January 2014 and December 2023. Data was collected from the local resuscitation registry and hospital electronic medical records. Neurological outcomes were measured using the Cerebral Performance Category (CPC) scale.</div><div><strong>Results</strong> At hospital admission return of spontaneous circulation (ROSC) was achieved in 36 % of cases (411/1128), with overall survival rates of 29 % (328/1128) at 24 h and 16 % (178/1128) at 30 days, respectively. Good neurological outcomes (CPC 1 and 2) were observed in 13 % (144/1128) of patients. The main suspected cause of cardiac arrest was cardiac origin (54 %, 608/1128), followed by hypoxia (11 %, 127/1128). Survivors were significantly younger (60 vs 71 years, <em>p</em> < 0.001), were less disabled (<em>p</em> < 0.001), had a higher incidence of witnessed cardiac arrest (80 % vs 69 %, <em>p</em> = 0.018), received more often bystander cardiopulmonary resuscitation (CPR, 62 % vs 47 %, <em>p</em> = 0.003) or Dispatcher Assisted-CPR (44 % vs 32 %, <em>p</em> = 0.004). Moreover, patients who survived at least 30 days had a higher incidence of shockable initial rhythm (57 % vs 24 %, <em>p</em> < 0.001).</div><div><strong>Conclusions</strong> Patients who survived at least 30 days were younger and male, had less disability, a shockable initial rhythm, and a cardiac arrest in public.</div></div>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"73 ","pages":"Pages 1-8"},"PeriodicalIF":2.4000,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Out-of-hospital cardiac arrest: A 10-year analysis of survival and neurological outcomes\",\"authors\":\"Daniel Schwaiger, Armin Krösbacher, Christine Eckhardt, Lukas Schausberger, Michael Baubin, Sasa Rajsic\",\"doi\":\"10.1016/j.hrtlng.2025.04.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div><strong>Background</strong> Out-of-hospital cardiac arrest (OHCA) is a major public health issue with low survival rates.</div><div><strong>Objective</strong> Identification of predictors for survival and good neurological outcomes following OHCA.</div><div><strong>Methods</strong> This retrospective study included all OHCA patients between January 2014 and December 2023. Data was collected from the local resuscitation registry and hospital electronic medical records. Neurological outcomes were measured using the Cerebral Performance Category (CPC) scale.</div><div><strong>Results</strong> At hospital admission return of spontaneous circulation (ROSC) was achieved in 36 % of cases (411/1128), with overall survival rates of 29 % (328/1128) at 24 h and 16 % (178/1128) at 30 days, respectively. Good neurological outcomes (CPC 1 and 2) were observed in 13 % (144/1128) of patients. The main suspected cause of cardiac arrest was cardiac origin (54 %, 608/1128), followed by hypoxia (11 %, 127/1128). Survivors were significantly younger (60 vs 71 years, <em>p</em> < 0.001), were less disabled (<em>p</em> < 0.001), had a higher incidence of witnessed cardiac arrest (80 % vs 69 %, <em>p</em> = 0.018), received more often bystander cardiopulmonary resuscitation (CPR, 62 % vs 47 %, <em>p</em> = 0.003) or Dispatcher Assisted-CPR (44 % vs 32 %, <em>p</em> = 0.004). Moreover, patients who survived at least 30 days had a higher incidence of shockable initial rhythm (57 % vs 24 %, <em>p</em> < 0.001).</div><div><strong>Conclusions</strong> Patients who survived at least 30 days were younger and male, had less disability, a shockable initial rhythm, and a cardiac arrest in public.</div></div>\",\"PeriodicalId\":55064,\"journal\":{\"name\":\"Heart & Lung\",\"volume\":\"73 \",\"pages\":\"Pages 1-8\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-04-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Heart & Lung\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0147956325000706\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Heart & Lung","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0147956325000706","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
摘要
院外心脏骤停(OHCA)是一个生存率低的主要公共卫生问题。目的确定OHCA术后生存和良好神经预后的预测因素。方法回顾性研究纳入2014年1月至2023年12月期间所有OHCA患者。数据收集自当地复苏登记和医院电子病历。神经学结果采用脑功能分类(CPC)量表进行测量。结果入院时,36%(411/1128)患者恢复了自发循环,24 h总生存率为29% (328/1128),30 d总生存率为16%(178/1128)。13%(144/1128)患者的神经系统预后良好(CPC 1和CPC 2)。怀疑心脏骤停的主要原因是心源性(54%,608/1128),其次是缺氧(11%,127/1128)。幸存者明显更年轻(60岁vs 71岁,p <;0.001),致残率较低(p <;0.001),目睹心脏骤停的发生率较高(80%对69%,p = 0.018),接受更多的旁观者心肺复苏(CPR, 62%对47%,p = 0.003)或调度员辅助心肺复苏(44%对32%,p = 0.004)。此外,存活至少30天的患者有更高的休克初始节律发生率(57% vs 24%, p <;0.001)。结论:存活至少30天的患者多为年轻男性,残疾较少,初始心律震荡,在公共场合心脏骤停。
Out-of-hospital cardiac arrest: A 10-year analysis of survival and neurological outcomes
Background Out-of-hospital cardiac arrest (OHCA) is a major public health issue with low survival rates.
Objective Identification of predictors for survival and good neurological outcomes following OHCA.
Methods This retrospective study included all OHCA patients between January 2014 and December 2023. Data was collected from the local resuscitation registry and hospital electronic medical records. Neurological outcomes were measured using the Cerebral Performance Category (CPC) scale.
Results At hospital admission return of spontaneous circulation (ROSC) was achieved in 36 % of cases (411/1128), with overall survival rates of 29 % (328/1128) at 24 h and 16 % (178/1128) at 30 days, respectively. Good neurological outcomes (CPC 1 and 2) were observed in 13 % (144/1128) of patients. The main suspected cause of cardiac arrest was cardiac origin (54 %, 608/1128), followed by hypoxia (11 %, 127/1128). Survivors were significantly younger (60 vs 71 years, p < 0.001), were less disabled (p < 0.001), had a higher incidence of witnessed cardiac arrest (80 % vs 69 %, p = 0.018), received more often bystander cardiopulmonary resuscitation (CPR, 62 % vs 47 %, p = 0.003) or Dispatcher Assisted-CPR (44 % vs 32 %, p = 0.004). Moreover, patients who survived at least 30 days had a higher incidence of shockable initial rhythm (57 % vs 24 %, p < 0.001).
Conclusions Patients who survived at least 30 days were younger and male, had less disability, a shockable initial rhythm, and a cardiac arrest in public.
期刊介绍:
Heart & Lung: The Journal of Cardiopulmonary and Acute Care, the official publication of The American Association of Heart Failure Nurses, presents original, peer-reviewed articles on techniques, advances, investigations, and observations related to the care of patients with acute and critical illness and patients with chronic cardiac or pulmonary disorders.
The Journal''s acute care articles focus on the care of hospitalized patients, including those in the critical and acute care settings. Because most patients who are hospitalized in acute and critical care settings have chronic conditions, we are also interested in the chronically critically ill, the care of patients with chronic cardiopulmonary disorders, their rehabilitation, and disease prevention. The Journal''s heart failure articles focus on all aspects of the care of patients with this condition. Manuscripts that are relevant to populations across the human lifespan are welcome.