Lucia Donno, Christian Dubbini, Carlo Albino Frigo
{"title":"步行时后稳定假体对膝关节韧带负荷的影响:一项肌肉骨骼模型研究","authors":"Lucia Donno, Christian Dubbini, Carlo Albino Frigo","doi":"10.1016/j.clinbiomech.2025.106526","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The correct balancing of the knee joint ligaments in case of total knee arthroplasty is fundamental for the functional outcome. Hence, it could be of interest for surgeons to understand how the ligaments' tension and intraarticular forces change after the implantation of a knee prosthesis, not only in clinical tests but particularly during functional activities. Many studies have compared the effects of different implant designs but without any reference to changes compared to the natural knee.</div></div><div><h3>Methods</h3><div>In this study, a posterior-stabilized prosthesis was virtually implanted in a three-dimensional musculoskeletal model of the knee joint. Through a dynamic simulation of the gait cycle, the knee kinematics, ligaments' tension and tibial-femoral contact force were quantified and compared with those obtained by the intact knee model.</div></div><div><h3>Findings</h3><div>In the presence of the prosthesis, the tibia preserved the two peaks of anterior displacement in correspondence with the peaks of knee flexion, even if reduced in relation to the intact knee. The superficial and deep Medial Collateral Ligaments supported the highest load, compensating for the absence of the cruciate ligaments. After the introduction of the prosthesis, the tibial-femoral contact force showed the same trend obtained in the natural knee model, however it appeared reduced compared to the intact knee condition and approached the experimental data recorded by an instrumented prosthesis.</div></div><div><h3>Interpretation</h3><div>This study quantified the changes induced by the posterior-stabilized implant in terms of kinematics, ligament tensions and intraarticular forces during walking, demonstrating how musculoskeletal models can support gaining insight into complex biomechanical systems.</div></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"125 ","pages":"Article 106526"},"PeriodicalIF":1.4000,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The effects of a posterior-stabilized prosthesis on knee ligament loads during walking: A musculoskeletal modelling study\",\"authors\":\"Lucia Donno, Christian Dubbini, Carlo Albino Frigo\",\"doi\":\"10.1016/j.clinbiomech.2025.106526\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>The correct balancing of the knee joint ligaments in case of total knee arthroplasty is fundamental for the functional outcome. Hence, it could be of interest for surgeons to understand how the ligaments' tension and intraarticular forces change after the implantation of a knee prosthesis, not only in clinical tests but particularly during functional activities. Many studies have compared the effects of different implant designs but without any reference to changes compared to the natural knee.</div></div><div><h3>Methods</h3><div>In this study, a posterior-stabilized prosthesis was virtually implanted in a three-dimensional musculoskeletal model of the knee joint. Through a dynamic simulation of the gait cycle, the knee kinematics, ligaments' tension and tibial-femoral contact force were quantified and compared with those obtained by the intact knee model.</div></div><div><h3>Findings</h3><div>In the presence of the prosthesis, the tibia preserved the two peaks of anterior displacement in correspondence with the peaks of knee flexion, even if reduced in relation to the intact knee. The superficial and deep Medial Collateral Ligaments supported the highest load, compensating for the absence of the cruciate ligaments. After the introduction of the prosthesis, the tibial-femoral contact force showed the same trend obtained in the natural knee model, however it appeared reduced compared to the intact knee condition and approached the experimental data recorded by an instrumented prosthesis.</div></div><div><h3>Interpretation</h3><div>This study quantified the changes induced by the posterior-stabilized implant in terms of kinematics, ligament tensions and intraarticular forces during walking, demonstrating how musculoskeletal models can support gaining insight into complex biomechanical systems.</div></div>\",\"PeriodicalId\":50992,\"journal\":{\"name\":\"Clinical Biomechanics\",\"volume\":\"125 \",\"pages\":\"Article 106526\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-04-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Biomechanics\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0268003325000993\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Biomechanics","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0268003325000993","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
The effects of a posterior-stabilized prosthesis on knee ligament loads during walking: A musculoskeletal modelling study
Background
The correct balancing of the knee joint ligaments in case of total knee arthroplasty is fundamental for the functional outcome. Hence, it could be of interest for surgeons to understand how the ligaments' tension and intraarticular forces change after the implantation of a knee prosthesis, not only in clinical tests but particularly during functional activities. Many studies have compared the effects of different implant designs but without any reference to changes compared to the natural knee.
Methods
In this study, a posterior-stabilized prosthesis was virtually implanted in a three-dimensional musculoskeletal model of the knee joint. Through a dynamic simulation of the gait cycle, the knee kinematics, ligaments' tension and tibial-femoral contact force were quantified and compared with those obtained by the intact knee model.
Findings
In the presence of the prosthesis, the tibia preserved the two peaks of anterior displacement in correspondence with the peaks of knee flexion, even if reduced in relation to the intact knee. The superficial and deep Medial Collateral Ligaments supported the highest load, compensating for the absence of the cruciate ligaments. After the introduction of the prosthesis, the tibial-femoral contact force showed the same trend obtained in the natural knee model, however it appeared reduced compared to the intact knee condition and approached the experimental data recorded by an instrumented prosthesis.
Interpretation
This study quantified the changes induced by the posterior-stabilized implant in terms of kinematics, ligament tensions and intraarticular forces during walking, demonstrating how musculoskeletal models can support gaining insight into complex biomechanical systems.
期刊介绍:
Clinical Biomechanics is an international multidisciplinary journal of biomechanics with a focus on medical and clinical applications of new knowledge in the field.
The science of biomechanics helps explain the causes of cell, tissue, organ and body system disorders, and supports clinicians in the diagnosis, prognosis and evaluation of treatment methods and technologies. Clinical Biomechanics aims to strengthen the links between laboratory and clinic by publishing cutting-edge biomechanics research which helps to explain the causes of injury and disease, and which provides evidence contributing to improved clinical management.
A rigorous peer review system is employed and every attempt is made to process and publish top-quality papers promptly.
Clinical Biomechanics explores all facets of body system, organ, tissue and cell biomechanics, with an emphasis on medical and clinical applications of the basic science aspects. The role of basic science is therefore recognized in a medical or clinical context. The readership of the journal closely reflects its multi-disciplinary contents, being a balance of scientists, engineers and clinicians.
The contents are in the form of research papers, brief reports, review papers and correspondence, whilst special interest issues and supplements are published from time to time.
Disciplines covered include biomechanics and mechanobiology at all scales, bioengineering and use of tissue engineering and biomaterials for clinical applications, biophysics, as well as biomechanical aspects of medical robotics, ergonomics, physical and occupational therapeutics and rehabilitation.