蜂窝废弃物碳点作为检测卡培他滨化疗药物的灵敏传感探针

IF 4.3 2区 化学 Q1 SPECTROSCOPY
Pradnya Khandagale , Prathamesh Chougale , Nafeesa Mujawar , Muskan Momin , Rohant Dhabbe , Rajratna Kakade , Sandip Nipane , Sandip Sabale , Deok-kee Kim
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引用次数: 0

摘要

抗癌药物因其过量对健康的不良影响而引起关注,因此,对其进行敏感监测至关重要。碳点(cd)是一种开创性的碳纳米材料,其颗粒小于10纳米。基于其发光特性,cd具有广泛的应用。当今时代的重点是将废物转化为经济上可行的产品。本研究为蜂窝废弃物制备绿色荧光CDs (HCCDs)提供了一种可行的方法。hccd显示出与激发相关的发射特性,随着激发波长的变化呈现蓝移,zeta电位为- 14.8 mV时具有良好的稳定性。然而,颗粒大小在2-5 nm之间。值得注意的是,由于络合物的形成,增加卡培他滨浓度的加入显著增强了hccd的荧光强度。在不受离子干扰的情况下,传感器的检测限为1.04 μmolL−1。该方法具有一定的选择性和敏感性,为卡培他滨药物的测定开辟了新的途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Honeycomb waste-derived carbon dots as a sensitive sensing probe for detection of capecitabine chemo drug

Honeycomb waste-derived carbon dots as a sensitive sensing probe for detection of capecitabine chemo drug
Anticancer medication provoked concerns owing to its adverse health effects from overdose and henceforth, its sensitive monitoring is crucial. Carbon dots (CDs), as a pioneering carbon nanomaterial, have particles lower than 10 nm. CDs have an extensive multitude of applications based on their luminous qualities. The present era is focused on turning waste into economically viable products. The current research demonstrates a feasible method for preparing green fluorescent CDs from honeycomb waste (HCCDs). The HCCDs display excitation-dependent emission properties, exhibiting a blue shift with a change in excitation wavelength, and acquiring good stability with a zeta potential of −14.8 mV. Nevertheless, the particle size ranges between 2–5 nm. It is noteworthy that the fluorescence intensity of HCCDs was remarkably enhanced by the addition of increasing concentrations of capecitabine due to complex formation. Additionally, the sensor shows a determined detection limit of 1.04 μmolL−1 without interference from ions. This demonstrates exclusive selectivity and sensitivity which paves a new way for the determination of the capecitabine drug.
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来源期刊
CiteScore
8.40
自引率
11.40%
发文量
1364
审稿时长
40 days
期刊介绍: Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (SAA) is an interdisciplinary journal which spans from basic to applied aspects of optical spectroscopy in chemistry, medicine, biology, and materials science. The journal publishes original scientific papers that feature high-quality spectroscopic data and analysis. From the broad range of optical spectroscopies, the emphasis is on electronic, vibrational or rotational spectra of molecules, rather than on spectroscopy based on magnetic moments. Criteria for publication in SAA are novelty, uniqueness, and outstanding quality. Routine applications of spectroscopic techniques and computational methods are not appropriate. Topics of particular interest of Spectrochimica Acta Part A include, but are not limited to: Spectroscopy and dynamics of bioanalytical, biomedical, environmental, and atmospheric sciences, Novel experimental techniques or instrumentation for molecular spectroscopy, Novel theoretical and computational methods, Novel applications in photochemistry and photobiology, Novel interpretational approaches as well as advances in data analysis based on electronic or vibrational spectroscopy.
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