接受BraveNet实践研究网络中西医结合疗效登记（primer）的患者：慢性疼痛队列的结果

IF 2.8 4区医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE

Integrative Medicine Research Pub Date : 2025-03-25 DOI:10.1016/j.imr.2025.101141

Jeffery A. Dusek , Qi Gao , Ryung S. Kim , Donald I. Abrams , Benjamin Kligler , Natalie L. Dyer , Kathryn Hansen , Eric J. Roseen , M. Diane McKee , the PRIMIER Writing Group*

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引用次数: 0

摘要

越来越多的诊所正在为慢性疼痛提供综合医学，这就产生了对现实世界、基于实践的研究的需求。我们的目的是对慢性疼痛患者报告的结果进行多地点前瞻性、基于实践的观察性评估。方法本研究在17家BraveNet基于实践的研究网络中西医结合诊所进行。在BraveNet诊所接受个性化综合医学干预的慢性疼痛患者符合条件。参与者在指数/基线访问和2、4、6和12个月时完成了患者报告结果测量信息系统-29、感知压力量表-4和患者激活测量。诊断和计费代码是从患者健康记录中提取的数据。线性混合模型和多变量分析评估了从索引访问到12个月的变化。结果共纳入4883例患者，其中3658例符合条件，其中967例认可慢性疼痛，在2个时间点完成至少2个结局，具有可评估的电子健康记录数据，并且在研究期间至少有一次中西医结合就诊。参与者的平均年龄为51.6岁（SD为13.88），主要是白人（81.8%）、女性（78.3%）、受过教育（≥大学学历：70.1%）。在12个月时，所有7个患者报告结果测量信息系统亚量表、感知压力量表和患者激活测量评分均有显著改善。结论在中西医结合诊所接受治疗的慢性疼痛患者在疼痛的多个领域和生活质量方面均有显著改善。未来有更多地点和一组共同结果的研究将进一步指导临床实践。临床试验注册。gov NCT01754038

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Patients Receiving Integrative Medicine Effectiveness Registry (PRIMIER) of the BraveNet practice-based research network: Results of the chronic pain cohort

Background

An increasing number of clinics are providing integrative medicine for chronic pain, creating a need for real-world, practice-based research. Our purpose was to conduct a multi-site prospective, practice-based, observational evaluation of patient reported outcomes in chronic pain patients.

Methods

This study took place at seventeen BraveNet Practice Based Research Network integrative medicine clinics. Chronic pain patients receiving personalized, integrative medicine interventions at BraveNet clinics were eligible. Participants completed the Patient Reported Outcomes Measurement Information System-29, Perceived Stress Scale-4, and the Patient Activation Measure at the index/baseline visit and at 2, 4, 6, and 12 months. Diagnostic and billing codes were extracted data from patients’ health records. Linear mixed-model and multi-variate analyses evaluated changes from index visit through 12 months.

Results

A total of 4883 patients enrolled, 3658 qualified and 967 of them endorsed chronic pain, completed at least two outcomes at 2 time points, had evaluable electronic health record data, and had at least one integrative medicine visit during the study period. Participants had a mean age of 51.6 years (SD 13.88) and were mostly white (81.8 %), female (78.3 %), educated (≥ college degree: 70.1 %). Significant improvements were observed on all 7 Patient Reported Outcomes Measurement Information System subscales, Perceived Stress Scale, and Patient Activation Measure scores at 12 months.

Conclusions

Chronic pain patients receiving care at integrative medicine clinics reported significant improvement over time in multiple domains of pain and quality of life. Future research with more sites and a common set of outcomes would further guide clinical practice.

Trial Registration

Clinical Trials.gov NCT01754038

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来源期刊

Integrative Medicine Research Medicine-Complementary and Alternative Medicine

CiteScore

6.50

自引率

2.90%

发文量

审稿时长

12 weeks

期刊介绍： Integrative Medicine Research (IMR) is a quarterly, peer-reviewed journal focused on scientific research for integrative medicine including traditional medicine (emphasis on acupuncture and herbal medicine), complementary and alternative medicine, and systems medicine. The journal includes papers on basic research, clinical research, methodology, theory, computational analysis and modelling, topical reviews, medical history, education and policy based on physiology, pathology, diagnosis and the systems approach in the field of integrative medicine.