Yao Lin , Yi Ye , Zhankuo Zhang , Xiaoyu Zi , Jinyi Zhang , Chengbin Zheng
{"title":"靶诱导光敏氧化法快速超灵敏检测四环素类抗生素","authors":"Yao Lin , Yi Ye , Zhankuo Zhang , Xiaoyu Zi , Jinyi Zhang , Chengbin Zheng","doi":"10.1016/j.snb.2025.137740","DOIUrl":null,"url":null,"abstract":"<div><div>Excessive use of tetracyclines (TCs) has led to their potential risks to public health and the environment. Therefore, rapid, accurate, and sensitive detection of TCs in environmental samples is crucial for ecological monitoring and safeguarding public health. However, the available colorimetric strategies based on peroxidase-like activity for the analysis of TCs usually involve nanomaterial synthesis and are limited by poor selectivity and sensitivity. In this study, we found that TCs characteristics with photocatalytic oxidation of chromogenic substrates induced by ultraviolet light. To further improve the selectivity of TCs-responsive colorimetry, Gd<sup>3 +</sup> was introduced to redshift the absorption of TCs to avoid the interference of substances that easily absorb ultraviolet light. Besides, nucleotide-Gd<sup>3+</sup> nanomaterials (GMP-Gd<sup>3+</sup>-NPs) was developed to achieve the concentration of TCs through simple mixing and centrifugation, allowing a highly sensitive TCs-responsive colorimetric detection. Under optimized conditions, the detection limits for tetracycline, oxytetracycline, and chlortetracycline were as low as 2.9 nM, 2.7 nM, and 4.3 nM, respectively. Compared to other colorimetric strategies, this developed GMP-Gd<sup>3+</sup>-TCs retains selectivity and excellent photocatalytic activity performance, providing great potential in the determination of TCs in environmental monitoring.</div></div>","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"439 ","pages":"Article 137740"},"PeriodicalIF":3.7000,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Target-induced photosensitization oxidation for rapid and ultrasensitive colorimetric detection of tetracycline antibiotics\",\"authors\":\"Yao Lin , Yi Ye , Zhankuo Zhang , Xiaoyu Zi , Jinyi Zhang , Chengbin Zheng\",\"doi\":\"10.1016/j.snb.2025.137740\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Excessive use of tetracyclines (TCs) has led to their potential risks to public health and the environment. Therefore, rapid, accurate, and sensitive detection of TCs in environmental samples is crucial for ecological monitoring and safeguarding public health. However, the available colorimetric strategies based on peroxidase-like activity for the analysis of TCs usually involve nanomaterial synthesis and are limited by poor selectivity and sensitivity. In this study, we found that TCs characteristics with photocatalytic oxidation of chromogenic substrates induced by ultraviolet light. To further improve the selectivity of TCs-responsive colorimetry, Gd<sup>3 +</sup> was introduced to redshift the absorption of TCs to avoid the interference of substances that easily absorb ultraviolet light. Besides, nucleotide-Gd<sup>3+</sup> nanomaterials (GMP-Gd<sup>3+</sup>-NPs) was developed to achieve the concentration of TCs through simple mixing and centrifugation, allowing a highly sensitive TCs-responsive colorimetric detection. Under optimized conditions, the detection limits for tetracycline, oxytetracycline, and chlortetracycline were as low as 2.9 nM, 2.7 nM, and 4.3 nM, respectively. Compared to other colorimetric strategies, this developed GMP-Gd<sup>3+</sup>-TCs retains selectivity and excellent photocatalytic activity performance, providing great potential in the determination of TCs in environmental monitoring.</div></div>\",\"PeriodicalId\":425,\"journal\":{\"name\":\"Sensors and Actuators B: Chemical\",\"volume\":\"439 \",\"pages\":\"Article 137740\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2025-04-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sensors and Actuators B: Chemical\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0925400525005155\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sensors and Actuators B: Chemical","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0925400525005155","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Target-induced photosensitization oxidation for rapid and ultrasensitive colorimetric detection of tetracycline antibiotics
Excessive use of tetracyclines (TCs) has led to their potential risks to public health and the environment. Therefore, rapid, accurate, and sensitive detection of TCs in environmental samples is crucial for ecological monitoring and safeguarding public health. However, the available colorimetric strategies based on peroxidase-like activity for the analysis of TCs usually involve nanomaterial synthesis and are limited by poor selectivity and sensitivity. In this study, we found that TCs characteristics with photocatalytic oxidation of chromogenic substrates induced by ultraviolet light. To further improve the selectivity of TCs-responsive colorimetry, Gd3 + was introduced to redshift the absorption of TCs to avoid the interference of substances that easily absorb ultraviolet light. Besides, nucleotide-Gd3+ nanomaterials (GMP-Gd3+-NPs) was developed to achieve the concentration of TCs through simple mixing and centrifugation, allowing a highly sensitive TCs-responsive colorimetric detection. Under optimized conditions, the detection limits for tetracycline, oxytetracycline, and chlortetracycline were as low as 2.9 nM, 2.7 nM, and 4.3 nM, respectively. Compared to other colorimetric strategies, this developed GMP-Gd3+-TCs retains selectivity and excellent photocatalytic activity performance, providing great potential in the determination of TCs in environmental monitoring.
期刊介绍:
Sensors & Actuators, B: Chemical is an international journal focused on the research and development of chemical transducers. It covers chemical sensors and biosensors, chemical actuators, and analytical microsystems. The journal is interdisciplinary, aiming to publish original works showcasing substantial advancements beyond the current state of the art in these fields, with practical applicability to solving meaningful analytical problems. Review articles are accepted by invitation from an Editor of the journal.