黏液物理限制甲型流感病毒颗粒进入上皮（Adv. Biology 4/2025）

IF 3.2 3区生物学 Q3 MATERIALS SCIENCE, BIOMATERIALS

Advanced biology Pub Date : 2025-04-16 DOI:10.1002/adbi.202570097

Logan Kaler, Elizabeth M. Engle, Maria Corkran, Ethan Iverson, Allison Boboltz, Maxinne A. Ignacio, Taj Yeruva, Margaret A. Scull, Gregg A. Duncan

{"title":"黏液物理限制甲型流感病毒颗粒进入上皮（Adv. Biology 4/2025）","authors":"Logan Kaler, Elizabeth M. Engle, Maria Corkran, Ethan Iverson, Allison Boboltz, Maxinne A. Ignacio, Taj Yeruva, Margaret A. Scull, Gregg A. Duncan","doi":"10.1002/adbi.202570097","DOIUrl":null,"url":null,"abstract":"<p><b>Influenza A</b></p><p>Mucus serves as a physical and adhesive barrier to infectious agents in the lung. The article number 2400329 by Gregg A. Duncan and co-workers demonstrates how the penetration of flu virus through the mucus barrier is significantly limited by the gel's internal microstructure and, to a lesser extent, by adhesive binding to mucin glycans.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":7234,"journal":{"name":"Advanced biology","volume":"9 4","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adbi.202570097","citationCount":"0","resultStr":"{\"title\":\"Mucus Physically Restricts Influenza A Viral Particle Access to the Epithelium (Adv. Biology 4/2025)\",\"authors\":\"Logan Kaler, Elizabeth M. Engle, Maria Corkran, Ethan Iverson, Allison Boboltz, Maxinne A. Ignacio, Taj Yeruva, Margaret A. Scull, Gregg A. Duncan\",\"doi\":\"10.1002/adbi.202570097\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><b>Influenza A</b></p><p>Mucus serves as a physical and adhesive barrier to infectious agents in the lung. The article number 2400329 by Gregg A. Duncan and co-workers demonstrates how the penetration of flu virus through the mucus barrier is significantly limited by the gel's internal microstructure and, to a lesser extent, by adhesive binding to mucin glycans.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":7234,\"journal\":{\"name\":\"Advanced biology\",\"volume\":\"9 4\",\"pages\":\"\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-04-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adbi.202570097\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/adbi.202570097\",\"RegionNum\":3,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced biology","FirstCategoryId":"99","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adbi.202570097","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}

引用次数: 0

摘要

流感粘液是肺部传染性病原体的物理和粘附屏障。Gregg a . Duncan及其同事发表的编号为2400329的文章表明，流感病毒通过黏液屏障的渗透是如何受到凝胶内部微观结构的显著限制的，在较小程度上，还受到粘蛋白聚糖粘附的限制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Mucus Physically Restricts Influenza A Viral Particle Access to the Epithelium (Adv. Biology 4/2025)

查看原文本刊更多论文

Mucus Physically Restricts Influenza A Viral Particle Access to the Epithelium (Adv. Biology 4/2025)

Influenza A

Mucus serves as a physical and adhesive barrier to infectious agents in the lung. The article number 2400329 by Gregg A. Duncan and co-workers demonstrates how the penetration of flu virus through the mucus barrier is significantly limited by the gel's internal microstructure and, to a lesser extent, by adhesive binding to mucin glycans.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Advanced biology Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

6.60

自引率

0.00%

发文量

130