D-lyxo-和d -xylo-植物旋光素和全酰化旋光素B的合成

IF 2.1 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2025-04-12 DOI:10.1016/j.tet.2025.134657

Gangarajulu Kesavulu, Kavirayani R. Prasad

引用次数: 0

摘要

介绍了合成D-lyxo和D-xylo-phytosphingosine及完全酰化鞘真菌素B甲酯的短合成序列。合成的关键反应是在亚亚胺中加入三（甲基硫）甲烷，以安装所需的手性氨基酸/氨基醇组分。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Total synthesis of D-lyxo- and D-xylo-phytospingosines and fully acylated sphingofungin B

查看原文本刊更多论文

Total synthesis of D-lyxo- and D-xylo-phytospingosines and fully acylated sphingofungin B

A short synthetic sequence for the synthesis of D-lyxo and D-xylo-phytosphingosine and fully acylated sphingofungin B methyl ester is presented. The key reaction in the synthesis is the addition of lithio tris(methylthio)methane to sulfinimine to install the required chiral amino acid/amino alcohol component.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.