The zeta potential for cancellous bone is calculated by poroelasticity

The zeta potential of cancellous bone is estimated by using poroelasticity. In colloidal chemistry, the zeta potential refers to the electric potential at the interface of the double layer. It is the potential difference between the stational layer on the solid bone matrix and interstitial fluid. The cancellous bone porosity, with a porosity of around 70–80 %, generates the peak of zeta potential in the wave propagation. If the zeta potential is small, attractive forces may exceed repulsive forces, and the aggregation of charged particles may be disrupted. If the zeta potential is significant, the charged molecules are stable and tend to aggregate. Thus, cancellous bone porosity, which ranges from 70 to 80 %, is ideal for the stability of charged molecules because a more significant zeta potential is required in this porosity range.