目前对III期局部晚期NSCLC可切除性的看法——胸外科医生的观点

IF 7.6 1区医学 Q1 ONCOLOGY

European Journal of Cancer Pub Date : 2025-04-13 DOI:10.1016/j.ejca.2025.115426

Clemens Aigner , Natalie Baldes , Merjem Begic , Fabian Doerr , Mir Alireza Hoda , Servet Bölükbas

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引用次数: 0

摘要

外科专业知识是决定可切除性的关键。由于外科专业知识的差异，与其他外科的合作，以及现有的技术设备，区分“标准可切除性”和“具有先进技术要求的可切除性”，可以为跨学科肿瘤板引入明确的决策算法。目前的2024 EORTC调查强调了在III期NSCLC的手术指征方面缺乏共识的领域。T4 NSCLC累及邻近结构应在MDT讨论后在高容量、有经验的中心进行治疗。未来的研究应侧重于完善局部晚期非小细胞肺癌的手术选择标准和优化治疗策略。

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Current perspective on resectability in stage III locally advanced NSCLC – The thoracic surgeons’ view

Surgical expertise is crucial in determining resectability. Due to differences in surgical expertise, cooperation with other surgical departments, and technical equipment available, a differentiation between “standard resectability” and “resectability with advanced technical requirements” can introduce a clear decision algorithm for interdisciplinary tumorboards. The current 2024 EORTC survey highlights areas with a lack of consensus on surgical indications in stage III NSCLC. T4 NSCLC with involvement of adjacent structures should be managed in high-volume, experienced centers following MDT discussion.

Future research should focus on refining selection criteria for surgery and optimize treatment strategies in patients with locally advanced NSCLC.

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来源期刊

European Journal of Cancer 医学-肿瘤学

CiteScore

11.50

自引率

4.80%

发文量

953

审稿时长

23 days

期刊介绍： The European Journal of Cancer (EJC) serves as a comprehensive platform integrating preclinical, digital, translational, and clinical research across the spectrum of cancer. From epidemiology, carcinogenesis, and biology to groundbreaking innovations in cancer treatment and patient care, the journal covers a wide array of topics. We publish original research, reviews, previews, editorial comments, and correspondence, fostering dialogue and advancement in the fight against cancer. Join us in our mission to drive progress and improve outcomes in cancer research and patient care.