Takayuki Harada , Tomohiro Shirasaka , Toshiaki Baba , Aya Mizusawa , Alfonso Villaroman , Rosalina Noguera-Caoile , Ma. Alodia Mercado , Jasmin Peralta , Keigo Hatto , Shogo Kanamori
{"title":"菲律宾针对甲基苯丙胺使用障碍患者的住院认知行为疗法与治疗社区:随机对照试验","authors":"Takayuki Harada , Tomohiro Shirasaka , Toshiaki Baba , Aya Mizusawa , Alfonso Villaroman , Rosalina Noguera-Caoile , Ma. Alodia Mercado , Jasmin Peralta , Keigo Hatto , Shogo Kanamori","doi":"10.1016/j.abrep.2025.100605","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>In the Philippines, an estimated 1.8 million people use methamphetamine. Despite the government’s anti-drug campaign, repressive methods have been ineffective. Thus, treatment and human services are needed. We developed a cognitive–behavioral therapy (CBT) program for residential and rehabilitation center-based treatment and examined its effectiveness<strong>.</strong></div></div><div><h3>Methods</h3><div>In this block-randomized single-blinded trial, control group participants received therapeutic community-type treatment only, while the intervention group additionally participated in our CBT program for 6 months. Primary outcomes were methamphetamine re-use, measured by urine tests and self-report at 3-months post-discharge, and self-reported well-being at pre-discharge and 3-months post-discharge.</div></div><div><h3>Findings</h3><div>Participants (n = 326) were randomized into intervention (n = 162) and control (n = 164) groups. At follow-up, 3/27 (11.11 %) and 1/27 (3.70 %) participants in the respective groups had positive urine tests for drug re-use (χ<sup>2</sup>(1) = 1.08, n.s., r = 0.037, 95 %CI [-0.064, 0.212]). The self-reported drug re-use rate was significantly higher in the intervention group (χ<sup>2</sup>(1) = 9.18, p < 0.01, r = 0.14 (95 %CI [0.050, 0.231]). However, pre-discharge self-rated health (F(1, 311) = 6.32, p < 0.025, η<sup>2</sup> = 0.02, 95 %CI [0.001, 0.06]) and problem-focused coping (F(1, 311) = 6.50, p < 0.025, η<sup>2</sup> = 0.021, 95 %CI [0.001, 0.06]) were significantly better among intervention group participants than among control participants.</div></div><div><h3>Conclusions</h3><div>Although without significant effect on drug re-use, the intervention had a small positive effect on patients’ well-being, coping skills, and other psychological variables. Additional research is required to develop effective treatments for methamphetamine use in this region.</div></div>","PeriodicalId":38040,"journal":{"name":"Addictive Behaviors Reports","volume":"21 ","pages":"Article 100605"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Residential cognitive–behavioral therapy versus therapeutic community for patients with methamphetamine use disorders in the Philippines: A randomized controlled trial\",\"authors\":\"Takayuki Harada , Tomohiro Shirasaka , Toshiaki Baba , Aya Mizusawa , Alfonso Villaroman , Rosalina Noguera-Caoile , Ma. Alodia Mercado , Jasmin Peralta , Keigo Hatto , Shogo Kanamori\",\"doi\":\"10.1016/j.abrep.2025.100605\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>In the Philippines, an estimated 1.8 million people use methamphetamine. Despite the government’s anti-drug campaign, repressive methods have been ineffective. Thus, treatment and human services are needed. We developed a cognitive–behavioral therapy (CBT) program for residential and rehabilitation center-based treatment and examined its effectiveness<strong>.</strong></div></div><div><h3>Methods</h3><div>In this block-randomized single-blinded trial, control group participants received therapeutic community-type treatment only, while the intervention group additionally participated in our CBT program for 6 months. Primary outcomes were methamphetamine re-use, measured by urine tests and self-report at 3-months post-discharge, and self-reported well-being at pre-discharge and 3-months post-discharge.</div></div><div><h3>Findings</h3><div>Participants (n = 326) were randomized into intervention (n = 162) and control (n = 164) groups. At follow-up, 3/27 (11.11 %) and 1/27 (3.70 %) participants in the respective groups had positive urine tests for drug re-use (χ<sup>2</sup>(1) = 1.08, n.s., r = 0.037, 95 %CI [-0.064, 0.212]). The self-reported drug re-use rate was significantly higher in the intervention group (χ<sup>2</sup>(1) = 9.18, p < 0.01, r = 0.14 (95 %CI [0.050, 0.231]). However, pre-discharge self-rated health (F(1, 311) = 6.32, p < 0.025, η<sup>2</sup> = 0.02, 95 %CI [0.001, 0.06]) and problem-focused coping (F(1, 311) = 6.50, p < 0.025, η<sup>2</sup> = 0.021, 95 %CI [0.001, 0.06]) were significantly better among intervention group participants than among control participants.</div></div><div><h3>Conclusions</h3><div>Although without significant effect on drug re-use, the intervention had a small positive effect on patients’ well-being, coping skills, and other psychological variables. 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Residential cognitive–behavioral therapy versus therapeutic community for patients with methamphetamine use disorders in the Philippines: A randomized controlled trial
Introduction
In the Philippines, an estimated 1.8 million people use methamphetamine. Despite the government’s anti-drug campaign, repressive methods have been ineffective. Thus, treatment and human services are needed. We developed a cognitive–behavioral therapy (CBT) program for residential and rehabilitation center-based treatment and examined its effectiveness.
Methods
In this block-randomized single-blinded trial, control group participants received therapeutic community-type treatment only, while the intervention group additionally participated in our CBT program for 6 months. Primary outcomes were methamphetamine re-use, measured by urine tests and self-report at 3-months post-discharge, and self-reported well-being at pre-discharge and 3-months post-discharge.
Findings
Participants (n = 326) were randomized into intervention (n = 162) and control (n = 164) groups. At follow-up, 3/27 (11.11 %) and 1/27 (3.70 %) participants in the respective groups had positive urine tests for drug re-use (χ2(1) = 1.08, n.s., r = 0.037, 95 %CI [-0.064, 0.212]). The self-reported drug re-use rate was significantly higher in the intervention group (χ2(1) = 9.18, p < 0.01, r = 0.14 (95 %CI [0.050, 0.231]). However, pre-discharge self-rated health (F(1, 311) = 6.32, p < 0.025, η2 = 0.02, 95 %CI [0.001, 0.06]) and problem-focused coping (F(1, 311) = 6.50, p < 0.025, η2 = 0.021, 95 %CI [0.001, 0.06]) were significantly better among intervention group participants than among control participants.
Conclusions
Although without significant effect on drug re-use, the intervention had a small positive effect on patients’ well-being, coping skills, and other psychological variables. Additional research is required to develop effective treatments for methamphetamine use in this region.
期刊介绍:
Addictive Behaviors Reports is an open-access and peer reviewed online-only journal offering an interdisciplinary forum for the publication of research in addictive behaviors. The journal accepts submissions that are scientifically sound on all forms of addictive behavior (alcohol, drugs, gambling, Internet, nicotine and technology) with a primary focus on behavioral and psychosocial research. The emphasis of the journal is primarily empirical. That is, sound experimental design combined with valid, reliable assessment and evaluation procedures are a requisite for acceptance. We are particularly interested in ''non-traditional'', innovative and empirically oriented research such as negative/null data papers, replication studies, case reports on novel treatments, and cross-cultural research. Studies that might encourage new lines of inquiry as well as scholarly commentaries on topical issues, systematic reviews, and mini reviews are also very much encouraged. We also welcome multimedia submissions that incorporate video or audio components to better display methodology or findings.