具有抗癌特性的铋-柚皮素纳米粒子的太阳能驱动光化学合成

IF 5.6 2区医学 Q1 BIOPHYSICS

Colloids and Surfaces B: Biointerfaces Pub Date : 2025-04-10 DOI:10.1016/j.colsurfb.2025.114699

Victoria Nephertiti Rodríguez-Chávez , Ingrid Guadalupe Meza-Pardo , Daniel Sánchez-Campos , Fernanda Abigail Silva-Melgarejo , Francisco Castillo-Rivera , Sarahí Josefina Estrada-Loredo , Daniela Salado-Leza

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引用次数: 0

摘要

采用直接的日光辅助光化学方法制备了铋-柚皮苷纳米颗粒，以提高柚皮苷的性能。所得到的二元胶体由大约30 纳米大小的半球形颗粒组成，表面带负电荷。利用各种光谱技术对络合进行了分析。通过MTT比色法测定人宫颈癌细胞，对柚皮苷和纳米粒子的抗癌特性进行了评价。BiNar显著降低了癌细胞的生存能力，强调了其治疗潜力。

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Solar-driven photochemical synthesis of bismuth-naringin nanoparticles with anticancer properties

Bismuth-naringin (BiNar) nanoparticles were developed using a straightforward sunlight-assisted photochemical method to enhance the properties of naringin. The resulting BiNar colloid consists in semi-spherical particles of approximately 30 nm in size with a negative surface charge. Complexation was elucidated using various spectrometric techniques. The anticancer properties of both naringin and the nanoparticles were evaluated by performing MTT colorimetric assays in human cervical cancer cells. BiNar significantly reduced the viability of cancer cells, underscoring its therapeutic potential.

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来源期刊

Colloids and Surfaces B: Biointerfaces 生物-材料科学：生物材料

CiteScore

11.10

自引率

3.40%

发文量

730

审稿时长

42 days

期刊介绍： Colloids and Surfaces B: Biointerfaces is an international journal devoted to fundamental and applied research on colloid and interfacial phenomena in relation to systems of biological origin, having particular relevance to the medical, pharmaceutical, biotechnological, food and cosmetic fields. Submissions that: (1) deal solely with biological phenomena and do not describe the physico-chemical or colloid-chemical background and/or mechanism of the phenomena, and (2) deal solely with colloid/interfacial phenomena and do not have appropriate biological content or relevance, are outside the scope of the journal and will not be considered for publication. The journal publishes regular research papers, reviews, short communications and invited perspective articles, called BioInterface Perspectives. The BioInterface Perspective provide researchers the opportunity to review their own work, as well as provide insight into the work of others that inspired and influenced the author. Regular articles should have a maximum total length of 6,000 words. In addition, a (combined) maximum of 8 normal-sized figures and/or tables is allowed (so for instance 3 tables and 5 figures). For multiple-panel figures each set of two panels equates to one figure. Short communications should not exceed half of the above. It is required to give on the article cover page a short statistical summary of the article listing the total number of words and tables/figures.