尼日利亚青少年和年轻成年人中的吸毒和共用针头现象：对一项多站点临床试验数据的横断面二次分析

IF 3.9 2区医学 Q1 PSYCHIATRY

Drug and alcohol dependence Pub Date : 2025-04-03 DOI:10.1016/j.drugalcdep.2025.112666

Simisola Agunbiade , Titilola Gbaja-Biamila , David Oladele , Chisom Obiezu-Umeh , Adesola Zaidat Musa , Lateef Akeem Blessing , Kadija Muse Tahlil , Folahanmi Tomiwa Akinsolu , Donaldson F. Conserve , Ebenezer Adeoti , Hong Xian , Kevin Kuriakose , Juliet Iwelunmor , Oliver Ezechi , Joseph Tucker

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引用次数: 0

摘要

在大多数低收入和中等收入国家，青少年和青壮年（14-24岁）的药物使用率最高。人们对尼日利亚亚裔青少年吸毒的原因知之甚少，减少伤害的服务也很有限。方法对尼日利亚涉及AYA的“I-TEST”研究的基线调查进行二次数据分析。值得关注的两个主要结局是终生药物使用测量和共用针头。进行逻辑回归分析以获得社会人口暴露与两个主要结局之间的比值比。比值比随后根据年龄和性别进行了调整。结果对1500份AYA问卷进行了分析。受访者大多是失业者、学生和生活在尼日利亚南部。有301/1500（20.3%）的AYA报告吸毒。其中213/301例（71.5%）报告共用针头。药物使用没有因年龄（OR:0.94, 95% CI: 0.73-1.22）或性别（OR:1.00, 95% CI: 0.77-1.28）而异。与尼日利亚西南地区相比，中北部地区的AYA吸毒几率（OR:1.86, 95% CI: 1.28-2.69）和共用针头的几率（OR:2.51, 95% CI: 1.07-5.91）更高。14-19岁的青少年共用针头的几率高于20-24岁的青少年（OR:3.49, 95% CI: 1.94-6.26）。与男性相比，女性AYA患者共用针头的几率更高（OR:5.05, 95% CI: 2.85-8.95）。结论尼日利亚青少年吸毒和共用针头现象较为普遍。目前迫切需要减少危害的服务和研究。

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Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial

Background

Adolescents and young adults (AYA, 14–24 years old) have the highest rates of drug use in most low- and middle-income countries. Little is known about the drivers of drug use among AYA in Nigeria and harm reduction services are limited.

Methods

A secondary data analysis was performed of the baseline survey of the ‘I-TEST’ study involving AYA in Nigeria. The two primary outcomes of interest were lifetime measures of drug use and needle sharing. Logistic regression analyses were performed to obtain odds ratios for the associations between socio-demographic exposures and the two primary outcomes. Odds ratios were subsequently adjusted for age and sex.

Results

1500 AYA survey responses were analysed. Respondents were mostly unemployed, students, and living in southern Nigeria. Drug use was reported by 301/1500(20.3 %) AYA. Among these, 213/301(71.5 %) reported needle sharing. Drug use did not vary by age (OR:0.94, 95 %CI:0.73–1.22) or sex (OR:1.00, 95 %CI:0.77–1.28). AYA in the North-Central zone had higher odds of drug use (OR:1.86, 95 %CI:1.28–2.69) and needle sharing (OR:2.51, 95 %CI:1.07–5.91) compared to AYA in the South-West zone of Nigeria. AYA aged 14–19 had higher odds of needle sharing compared to those aged 20–24 (OR:3.49, 95 %CI:1.94–6.26). Female AYA had higher odds of needle sharing compared to males (OR:5.05, 95 %CI:2.85–8.95).

Conclusions

Drug use and needle sharing are common among AYA in Nigeria. There is an urgent need for harm reduction services and research informed by AYA.

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来源期刊

Drug and alcohol dependence 医学-精神病学

CiteScore

7.40

自引率

7.10%

发文量

409

审稿时长

41 days

期刊介绍： Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.