拉斯穆森脑炎和下肢局部硬皮病：另一块拼图。一份病例报告和文献综述，包含个体参与者数据

IF 2.5 4区医学 Q3 IMMUNOLOGY

Journal of neuroimmunology Pub Date : 2025-04-03 DOI:10.1016/j.jneuroim.2025.578608

Adolfo Mazzeo , Emanuele Cerulli Irelli , Alessandra Morano , Pierpaolo Quarato , Giancarlo Di Gennaro , Carlo Di Bonaventura

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引用次数: 0

摘要

拉斯穆森脑炎（RE）和局限性硬皮病（LS）的共同发生是罕见的和鲜为人知的。我们描述了一名23岁的右半球迟发性RE的独特病例，出现在左下肢LS后15年。此外，通过对现有文献的系统回顾，我们描述了RE伴发LS的明显特征：与经典RE病例相比，其发病延迟；其出现在LS之前或之后；以及同侧或对侧半球对受累颅面皮肤的不同受累程度。这些发现可能会为这两种情况之间的相互作用提供一些线索。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Rasmussen encephalitis and localized scleroderma of the lower limb: Another piece of the puzzle. A case-report and literature review with individual participant data

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Rasmussen encephalitis and localized scleroderma of the lower limb: Another piece of the puzzle. A case-report and literature review with individual participant data

The co-occurrence of Rasmussen encephalitis (RE) and localized scleroderma (LS) is rare and poorly known. We describe the unique case of a 23-year-old patient with late-onset RE of the right hemisphere, emerging 15 years following LS of the left lower limb exclusively.

Furthermore, through a systematic review of existing literature, we delineate distinct characteristics of RE concomitant with LS: a delayed onset compared to classical RE cases; its occurrence either preceding or succeeding LS; and the variable involvement of the ipsilateral or contralateral hemisphere to the affected craniofacial skin. These findings might provide some hints regarding the interplay between these two conditions.

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来源期刊

Journal of neuroimmunology 医学-免疫学

CiteScore

6.10

自引率

3.00%

发文量

154

审稿时长

37 days

期刊介绍： The Journal of Neuroimmunology affords a forum for the publication of works applying immunologic methodology to the furtherance of the neurological sciences. Studies on all branches of the neurosciences, particularly fundamental and applied neurobiology, neurology, neuropathology, neurochemistry, neurovirology, neuroendocrinology, neuromuscular research, neuropharmacology and psychology, which involve either immunologic methodology (e.g. immunocytochemistry) or fundamental immunology (e.g. antibody and lymphocyte assays), are considered for publication.