Katie Lattanzio, Khalid Alkhatib, Tom Guzzo, Daniel J. Lee, Phil Pierorazio, Trinity Bivalacqua, Ben Schurhamer
{"title":"案例研究:脉冲电场消融术治疗前列腺癌","authors":"Katie Lattanzio, Khalid Alkhatib, Tom Guzzo, Daniel J. Lee, Phil Pierorazio, Trinity Bivalacqua, Ben Schurhamer","doi":"10.1016/j.eucr.2025.103023","DOIUrl":null,"url":null,"abstract":"<div><div>Pulsed Electric Field (PEF) ablation is an emerging non-thermal ablation device with previous uses in lung, liver and sarcoma cancers. We present a case of prostate cancer recurrence post-radiation managed with PEF ablation. Under transperineal guidance, targeted PEF was delivered to the area of concern on previous biopsies and PSMA. In follow up the patient had a marked decline in PSA levels and resolution on follow-up PSMA. The patient experienced no significant side effects, preserving urinary continence and sexual function. These outcomes underscore PEF ablation's potential as a safe and effective salvage therapy with minimal impact on quality of life.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"60 ","pages":"Article 103023"},"PeriodicalIF":0.5000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Case study: Pulsed electric field ablation for salvage prostate cancer ablation\",\"authors\":\"Katie Lattanzio, Khalid Alkhatib, Tom Guzzo, Daniel J. Lee, Phil Pierorazio, Trinity Bivalacqua, Ben Schurhamer\",\"doi\":\"10.1016/j.eucr.2025.103023\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Pulsed Electric Field (PEF) ablation is an emerging non-thermal ablation device with previous uses in lung, liver and sarcoma cancers. We present a case of prostate cancer recurrence post-radiation managed with PEF ablation. Under transperineal guidance, targeted PEF was delivered to the area of concern on previous biopsies and PSMA. In follow up the patient had a marked decline in PSA levels and resolution on follow-up PSMA. The patient experienced no significant side effects, preserving urinary continence and sexual function. These outcomes underscore PEF ablation's potential as a safe and effective salvage therapy with minimal impact on quality of life.</div></div>\",\"PeriodicalId\":38188,\"journal\":{\"name\":\"Urology Case Reports\",\"volume\":\"60 \",\"pages\":\"Article 103023\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-03-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214442025000944\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214442025000944","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Case study: Pulsed electric field ablation for salvage prostate cancer ablation
Pulsed Electric Field (PEF) ablation is an emerging non-thermal ablation device with previous uses in lung, liver and sarcoma cancers. We present a case of prostate cancer recurrence post-radiation managed with PEF ablation. Under transperineal guidance, targeted PEF was delivered to the area of concern on previous biopsies and PSMA. In follow up the patient had a marked decline in PSA levels and resolution on follow-up PSMA. The patient experienced no significant side effects, preserving urinary continence and sexual function. These outcomes underscore PEF ablation's potential as a safe and effective salvage therapy with minimal impact on quality of life.