Mingyao Wang, Xiao Yang, Tingting Gou, Tao Huang, Xiaoling Wang*, Qichang Yang and Junling Guo*,
{"title":"化学动力学金属-酚类纳米农药对植物病原体进行原位过氧化氢自供,以实现食品可持续性","authors":"Mingyao Wang, Xiao Yang, Tingting Gou, Tao Huang, Xiaoling Wang*, Qichang Yang and Junling Guo*, ","doi":"10.1021/acssuschemeng.5c0173910.1021/acssuschemeng.5c01739","DOIUrl":null,"url":null,"abstract":"<p >The growing reliance on pesticides for food sustainability has led to environmental pollution and food safety concerns. Herein, we present a chemodynamic strategy using a Fenton-type nanopesticide, referred to as metal-phenolic ROS-nanogenerator (nanoRSG), to enhance the control of two widely spreading plant pathogens (<i>Pseudomonas syringae</i> and <i>Fusarium oxysporum</i>). The nanoRSG is constructed by the supramolecular self-assembly of natural polyphenols and Cu<sup>2+</sup> ions, followed by an in situ transition into phenolic-stabilized CuO<sub>2</sub> nanoclusters with the aid of hydroxide ions in the presence of H<sub>2</sub>O<sub>2</sub>. Subsequently, the nanoRSG decomposes in the pathogenic-relevant microenvironment into Fenton-catalyzed H<sub>2</sub>O<sub>2</sub> and Cu<sup>2+</sup> ions, followed by the highly efficient Fenton reactions for generating •O<sub>2</sub><sup>–</sup> to damage pathogenic cell membranes. Regarding curative effects on tomato leaves against <i>P. syringae</i> and <i>F. oxysporum</i>, nanoRSG outperforms the commercial Kocide 3000 formulations with 94.7 and 86.9% increasing efficacy, respectively. Moreover, for curative activity on tomato roots, nanoRSG also has a better performance (87.8 and 78.9%) than Kocide 3000 (31.3 and 43.9%). Besides, the biosafety of nanoRSG is confirmed by toxicity tests in zebrafish and lettuce cultivation in a field test of hydroponics. Our findings demonstrate that the metal-phenolic nanoenabled strategy offers a promising formulation for innovating conventional pesticides and enhancing food sustainability.</p>","PeriodicalId":25,"journal":{"name":"ACS Sustainable Chemistry & Engineering","volume":"13 14","pages":"5467–5478 5467–5478"},"PeriodicalIF":7.3000,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Chemodynamic Metal-Phenolic Nanopesticide Performs In Situ Hydrogen Peroxide Self-Supply against Plant Pathogens for Food Sustainability\",\"authors\":\"Mingyao Wang, Xiao Yang, Tingting Gou, Tao Huang, Xiaoling Wang*, Qichang Yang and Junling Guo*, \",\"doi\":\"10.1021/acssuschemeng.5c0173910.1021/acssuschemeng.5c01739\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >The growing reliance on pesticides for food sustainability has led to environmental pollution and food safety concerns. Herein, we present a chemodynamic strategy using a Fenton-type nanopesticide, referred to as metal-phenolic ROS-nanogenerator (nanoRSG), to enhance the control of two widely spreading plant pathogens (<i>Pseudomonas syringae</i> and <i>Fusarium oxysporum</i>). The nanoRSG is constructed by the supramolecular self-assembly of natural polyphenols and Cu<sup>2+</sup> ions, followed by an in situ transition into phenolic-stabilized CuO<sub>2</sub> nanoclusters with the aid of hydroxide ions in the presence of H<sub>2</sub>O<sub>2</sub>. Subsequently, the nanoRSG decomposes in the pathogenic-relevant microenvironment into Fenton-catalyzed H<sub>2</sub>O<sub>2</sub> and Cu<sup>2+</sup> ions, followed by the highly efficient Fenton reactions for generating •O<sub>2</sub><sup>–</sup> to damage pathogenic cell membranes. Regarding curative effects on tomato leaves against <i>P. syringae</i> and <i>F. oxysporum</i>, nanoRSG outperforms the commercial Kocide 3000 formulations with 94.7 and 86.9% increasing efficacy, respectively. Moreover, for curative activity on tomato roots, nanoRSG also has a better performance (87.8 and 78.9%) than Kocide 3000 (31.3 and 43.9%). Besides, the biosafety of nanoRSG is confirmed by toxicity tests in zebrafish and lettuce cultivation in a field test of hydroponics. Our findings demonstrate that the metal-phenolic nanoenabled strategy offers a promising formulation for innovating conventional pesticides and enhancing food sustainability.</p>\",\"PeriodicalId\":25,\"journal\":{\"name\":\"ACS Sustainable Chemistry & Engineering\",\"volume\":\"13 14\",\"pages\":\"5467–5478 5467–5478\"},\"PeriodicalIF\":7.3000,\"publicationDate\":\"2025-04-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Sustainable Chemistry & Engineering\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://pubs.acs.org/doi/10.1021/acssuschemeng.5c01739\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Sustainable Chemistry & Engineering","FirstCategoryId":"92","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acssuschemeng.5c01739","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Chemodynamic Metal-Phenolic Nanopesticide Performs In Situ Hydrogen Peroxide Self-Supply against Plant Pathogens for Food Sustainability
The growing reliance on pesticides for food sustainability has led to environmental pollution and food safety concerns. Herein, we present a chemodynamic strategy using a Fenton-type nanopesticide, referred to as metal-phenolic ROS-nanogenerator (nanoRSG), to enhance the control of two widely spreading plant pathogens (Pseudomonas syringae and Fusarium oxysporum). The nanoRSG is constructed by the supramolecular self-assembly of natural polyphenols and Cu2+ ions, followed by an in situ transition into phenolic-stabilized CuO2 nanoclusters with the aid of hydroxide ions in the presence of H2O2. Subsequently, the nanoRSG decomposes in the pathogenic-relevant microenvironment into Fenton-catalyzed H2O2 and Cu2+ ions, followed by the highly efficient Fenton reactions for generating •O2– to damage pathogenic cell membranes. Regarding curative effects on tomato leaves against P. syringae and F. oxysporum, nanoRSG outperforms the commercial Kocide 3000 formulations with 94.7 and 86.9% increasing efficacy, respectively. Moreover, for curative activity on tomato roots, nanoRSG also has a better performance (87.8 and 78.9%) than Kocide 3000 (31.3 and 43.9%). Besides, the biosafety of nanoRSG is confirmed by toxicity tests in zebrafish and lettuce cultivation in a field test of hydroponics. Our findings demonstrate that the metal-phenolic nanoenabled strategy offers a promising formulation for innovating conventional pesticides and enhancing food sustainability.
期刊介绍:
ACS Sustainable Chemistry & Engineering is a prestigious weekly peer-reviewed scientific journal published by the American Chemical Society. Dedicated to advancing the principles of green chemistry and green engineering, it covers a wide array of research topics including green chemistry, green engineering, biomass, alternative energy, and life cycle assessment.
The journal welcomes submissions in various formats, including Letters, Articles, Features, and Perspectives (Reviews), that address the challenges of sustainability in the chemical enterprise and contribute to the advancement of sustainable practices. Join us in shaping the future of sustainable chemistry and engineering.