钯/降冰片烯协同催化三功能化：杂芳基碘化物的氨基酰化/双环化

IF 4.3 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-04-11 DOI:10.1039/d5cc00294j

Yi-Xin Chai, Yu-Fan Yang, Feng-Yu Zhang, Ji-Yan Zhao, Ya-Ting Wang, Yanmei Chen, Yuan-Yuan Sun, Jin-Heng Li, Yan-Ping Zhu

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引用次数: 0

摘要

报道了一种新的Pd/ nbe催化的杂芳基碘化物分子间脱氢双氧化反应，用于合成多环含氮杂环。在这项工作中，n保护的芳基氨基甲酰氯作为酰化的来源。杂芳基碘化物直接碳氢官能化产物制备顺利，无杂原子催化中毒。

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Palladium/norbornene cooperative catalysis triple functionalization: carbamoylation/double-annulation of (hetero)aryl iodides

A novel Pd/NBE-catalyzed intermolecular dehydrobicyclization of heteroaryl iodides for the synthesis of polycyclic nitrogen-containing heterocycles is reported. In this work, the N-protected aryl carbamoyl chloride serves as a source of acylation. The products resulting from the direct C–H functionalization of heteroaryl iodides are smoothly obtained without catalyst poisoning by heteroatom.

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.