光诱导镍催化的单氟、宝石二氟和三氟甲基系连烯烃的碳卤化反应

IF 4.3 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-04-11 DOI:10.1039/d5cc01034a

Ruchi Sharma, Naveen Sihag, Poorvi Gupta, Kuntal Manna, M. Ramu Yadav

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引用次数: 0

摘要

光激发镍催化的氟烯烃碳卤化反应得到了具有季中心的卤代氟烷基氧吲哚。广泛的衬底范围，保留氟原子，然后是碘-宝石-二氟烷基氧吲哚的有效合成转化，突出了这种方法的优点。此外，还进行了控制实验和DFT计算来阐明镍催化剂三重激发态的意义。

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Photoinduced Ni-Catalyzed Carbohalogenation of mono-Fluoro, gem-Difluoro, and Trifluoromethyl Tethered Alkenes

Photoexcited nickel-catalyzed carbohalogenation reaction of fluoroalkenes has been demonstrated to afford halofluoroalkyl oxindoles featuring a quaternary center. The broad substrate scope with retention of fluorine atoms followed by efficient synthetic transformations of iodo-gem-difluoroalkyl oxindoles highlight the advantages of this methodology. Additionally, control experiments and DFT calculations have been conducted to illuminate the significance of the triplet-excited state of the nickel catalyst.

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.