怀孕期间药物使用的知识、态度和实践：西乌干达的横断面研究

IF 2.1 Q2 MEDICINE, GENERAL & INTERNAL

Health Science Reports Pub Date : 2025-04-10 DOI:10.1002/hsr2.70644

Musiime Brian, Narayana Goruntla, Bhavana Reddy Bommireddy, Bhavani Mopuri, Easwaran Vigneshwaran, Mohammad Jaffar Sadiq Mantargi, Vishnuvandana Bandaru, Joseph Obiezu Chukwujekwu Ezeonwumelu, Sarad Pawar Naik Bukke, Tadele Mekuriya Yadesa, Ebere Emilia Ayogu

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引用次数: 0

摘要

背景：怀孕期间药物使用（MU）会增加孕妇和胎儿健康后果的风险。妇女关于安全MU的知识、态度和实践（KAP）可以影响妊娠结局。该研究旨在评估和探讨妇女在怀孕期间安全MU的KAP，并确定可能的决定因素。方法对在乌干达西部凯盖瓜区凯盖瓜总医院妇产科接受产前护理（ANC）的孕妇进行横断面分析式访谈调查。采用预先设计的24项结构化问卷评估孕妇MU的KAP。采用二元和多元logistic回归分析确定与MU相关的KAP因素。结果共纳入415例孕妇，平均（SD）年龄26.51（5.15）岁。大多数妇女对安全MU持积极态度（78.60%），但仅有42.60%的妇女对MU有充分的了解，34.50%的妇女对MU有合理的操作。中等及以下教育程度等因素(AOR = 0.15；95%可信区间= 0.01 - -0.38),城市住宅(优势比= 1.54;95% CI = 2.68-4.49)，职业(AOR = 1.94；95% CI = 2.36-10.59)，定期ANC就诊(AOR = 1.22；95% CI = 1.06-3.48)，妊娠期全科医生就诊(AOR = 2.54；95% CI = 1.09-5.91)，并且至少使用一种药物(AOR = 9.00；95% CI = 2.78-6.43)与MU知识的充分相关。执业领域显示年龄小于30岁(AOR = 0.53；95% CI = 0.28-0.98)、职业(AOR = 2.56；95% CI = 1.86-7.59)，定期ANC就诊(AOR = 1.79；95% CI = 1.05-3.74)，妊娠期全科医生就诊(AOR = 1.73；95% CI = 1.02-3.25)与理性实践显著相关。结论：四分之三的孕妇对安全MU有积极的态度，但由于缺乏足够的知识，在将这种积极的态度转化为合理的做法方面还有很大的差距。因此，为了解决在知识和实践领域发现的差距，可以针对年轻人、低学历或无学历、农村居民和从事非医疗保健专业的参与者启动基于医院的安全MU教育干预。

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Knowledge, Attitude, and Practice of Medication Use During Pregnancy: A Cross-Sectional Study in Western Uganda

Background

Medication use (MU) during pregnancy can increase the risk of maternal and fetal health consequences. Women's knowledge, attitude, and practice (KAP) regarding safe MU can influence pregnancy outcomes. The study aimed to assess and explore women's KAP regarding safe MU during pregnancy and identify possible determinants.

Methods

A cross-sectional analytical, interview-based survey was conducted among pregnant women attending antenatal care (ANC) visits in the obstetrics and gynaecology department of Kyegegwa General Hospital, Kyegegwa district, Western Uganda. A 24-item pre-designed, validated structured questionnaire was used to assess the KAP of MU among pregnant women. Binary and multiple logistic regression analyses were used to identify factors associated with KAP about MU.

Results

A total of 415 pregnant women with a mean (SD) age of 26.51 (5.15) years were included. Most of the women have a positive attitude (78.60%) towards safe MU, but less than half only hold adequate knowledge (42.60%), and rational practice (34.50%). Factors such as secondary education level or less (AOR = 0.15; 95% CI = 0.01–0.38), urban residence (AOR = 1.54; 95% CI = 2.68–4.49), profession (AOR = 1.94; 95% CI = 2.36–10.59), regular ANC visits (AOR = 1.22; 95% CI = 1.06–3.48), GP visit during pregnancy (AOR = 2.54; 95% CI = 1.09–5.91), and using at least one medication (AOR = 9.00; 95% CI = 2.78–6.43) were significantly associated with adequate knowledge regarding MU. The practice domain revealed that age less than 30 years (AOR = 0.53; 95% CI = 0.28–0.98), profession (AOR = 2.56; 95% CI = 1.86–7.59), regular ANC visits (AOR = 1.79; 95% CI = 1.05–3.74), and GP visit during pregnancy (AOR = 1.73; 95% CI = 1.02–3.25) were significantly associated with rational practice.

Conclusion

The study concludes that three-fourths of the pregnant women have a positive attitude regarding safe MU, still there is an extensive gap in transforming this positive attitude into rational practice due to lack of adequate knowledge. So, to address the gap identified in the knowledge and practice domain, hospital-based educational interventions on safe MU can be initiated by targeting young age, lower or no education, rural residents, and participants working in non-healthcare profession.

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