{"title":"铁铜纳米粒子修饰磷酸钙涂层:增强抗菌和生物相容性","authors":"V. V. Chebodaeva, O. V. Bakina, Yu. P. Sharkeev","doi":"10.1007/s11182-025-03395-2","DOIUrl":null,"url":null,"abstract":"<div><p>Calcium phosphate (CaP) coatings modified with Fe–Cu nanoparticles have been manufactured using the micro-arc oxidation (MAO) method. The primary focus was on the morphology, elemental composition, phase composition, and surface charge properties as well as the antimicrobial activity and cytotoxicity of the coatings. It is demonstrated that the addition of the Fe–Cu nanoparticles enhances the antimicrobial properties of the coatings by reducing the number of viable Staphylococcus aureus bacteria and increases the biocompatibility of the coatings. This makes the coatings promising for use in medical implants, providing the necessary composition and porosity along with the improved biological characteristics.</p></div>","PeriodicalId":770,"journal":{"name":"Russian Physics Journal","volume":"68 1","pages":"16 - 23"},"PeriodicalIF":0.4000,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fe–Cu nanoparticle-modified calcium phosphate coatings: enhanced antimicrobial and biocompatibility properties\",\"authors\":\"V. V. Chebodaeva, O. V. Bakina, Yu. P. Sharkeev\",\"doi\":\"10.1007/s11182-025-03395-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Calcium phosphate (CaP) coatings modified with Fe–Cu nanoparticles have been manufactured using the micro-arc oxidation (MAO) method. The primary focus was on the morphology, elemental composition, phase composition, and surface charge properties as well as the antimicrobial activity and cytotoxicity of the coatings. It is demonstrated that the addition of the Fe–Cu nanoparticles enhances the antimicrobial properties of the coatings by reducing the number of viable Staphylococcus aureus bacteria and increases the biocompatibility of the coatings. This makes the coatings promising for use in medical implants, providing the necessary composition and porosity along with the improved biological characteristics.</p></div>\",\"PeriodicalId\":770,\"journal\":{\"name\":\"Russian Physics Journal\",\"volume\":\"68 1\",\"pages\":\"16 - 23\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-02-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Physics Journal\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s11182-025-03395-2\",\"RegionNum\":4,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHYSICS, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Physics Journal","FirstCategoryId":"101","ListUrlMain":"https://link.springer.com/article/10.1007/s11182-025-03395-2","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHYSICS, MULTIDISCIPLINARY","Score":null,"Total":0}
Fe–Cu nanoparticle-modified calcium phosphate coatings: enhanced antimicrobial and biocompatibility properties
Calcium phosphate (CaP) coatings modified with Fe–Cu nanoparticles have been manufactured using the micro-arc oxidation (MAO) method. The primary focus was on the morphology, elemental composition, phase composition, and surface charge properties as well as the antimicrobial activity and cytotoxicity of the coatings. It is demonstrated that the addition of the Fe–Cu nanoparticles enhances the antimicrobial properties of the coatings by reducing the number of viable Staphylococcus aureus bacteria and increases the biocompatibility of the coatings. This makes the coatings promising for use in medical implants, providing the necessary composition and porosity along with the improved biological characteristics.
期刊介绍:
Russian Physics Journal covers the broad spectrum of specialized research in applied physics, with emphasis on work with practical applications in solid-state physics, optics, and magnetism. Particularly interesting results are reported in connection with: electroluminescence and crystal phospors; semiconductors; phase transformations in solids; superconductivity; properties of thin films; and magnetomechanical phenomena.