Ahmed Elzein, Ghadah Abdullah S. Al Jomeh, Graham J. Tizzard, Simon J. Coles, Christina N. Banti, Sotiris K. Hadjikakou and George E. Kostakis
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Investigating the antimicrobial activity of 1-heteroaryl benzotriazole silver compounds†
Five (1–5) Ag(I) compounds, derived from different N,N′-bidentate 1-heteroaryl benzotriazole ligands, were synthesised and characterised using SXRD, IR, UV-Vis, elemental analysis, ESI-MS, and NMR. Variations in ligands and counter-anions produced distinct structures and morphologies. Preliminary antimicrobial testing at the micromolar level, in DMSO, revealed that only compound 2, based on 1-(2-pyridyl)benzotriazole and triflate anion, exhibited interesting antimicrobial properties, thus marking the introduction of a new class of Ag(I) compounds in medicinal inorganic chemistry.
期刊介绍:
An international, peer-reviewed journal covering all of the chemical sciences, including multidisciplinary and emerging areas. RSC Advances is a gold open access journal allowing researchers free access to research articles, and offering an affordable open access publishing option for authors around the world.