蜂胶：对大自然的多酚奇迹的全面回顾

IF 2.5 3区医学 Q3 CHEMISTRY, MEDICINAL

Fitoterapia Pub Date : 2025-04-07 DOI:10.1016/j.fitote.2025.106526

Arun Kumar Balasubramaniam , Ashmitha Elangovan , Maheen Abdul Rahman , Subhendu Nayak , Durga Swain , Harathi Parasur Babu , Aarthi Narasimhan , Vikramdeep Monga

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引用次数: 0

摘要

蜂胶是一种由蜜蜂生产的树脂状物质，由于其多种生物活性，几个世纪以来一直被用于传统医学。本文综述了蜂胶的植物化学成分、治疗应用和潜在的健康益处。蜂胶由树脂、蜡、精油和花粉的复杂混合物组成，具有显著的抗菌、抗氧化、抗炎、免疫调节和抗癌特性。蜂胶的植物化学成分因其植物和地理来源而异，影响其生物活性。蜂胶在伤口愈合、口腔健康、心血管保护、神经保护、肝脏保护和胃肠道健康方面显示出良好的前景。尽管它具有治疗潜力，但需要解决标准化、质量控制和监管问题等挑战。未来的研究应重点阐明其作用机制，优化提取方法，并进行广泛的临床试验以验证其有效性和安全性。可持续生产和保护工作是保证持续供应高质量蜂胶的必要条件。这篇综述强调了跨学科研究的必要性，以充分利用蜂胶在现代医学中的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Propolis: A comprehensive review on the nature's polyphenolic wonder

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Propolis: A comprehensive review on the nature's polyphenolic wonder

Propolis, a resinous substance produced by honeybees, has been utilized in traditional medicine for centuries due to its diverse biological activities. This review explores the phytochemical composition, therapeutic applications, and potential health benefits of propolis. Comprising a complex mixture of resins, waxes, essential oils, and pollen, propolis exhibits significant antimicrobial, antioxidant, anti-inflammatory, immunomodulatory, and anticancer properties. The phytochemical content of propolis varies with its botanical and geographical origins, influencing its bioactivity. Propolis has shown promise in wound healing, oral health, cardiovascular protection, neuroprotection, hepatoprotection, and gastrointestinal health. Despite its therapeutic potential, challenges such as standardization, quality control, and regulatory issues need to be addressed. Future research should focus on elucidating the mechanisms of action, optimizing extraction methods, and conducting extensive clinical trials to validate its efficacy and safety. Sustainable production and conservation efforts are essential to ensure the continuous supply of high- quality propolis. This review highlights the need for interdisciplinary research to fully harness the potential of propolis in modern medicine.

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来源期刊

Fitoterapia 医学-药学

CiteScore

5.80

自引率

2.90%

发文量

198

审稿时长

1.5 months

期刊介绍： Fitoterapia is a Journal dedicated to medicinal plants and to bioactive natural products of plant origin. It publishes original contributions in seven major areas: 1. Characterization of active ingredients of medicinal plants 2. Development of standardization method for bioactive plant extracts and natural products 3. Identification of bioactivity in plant extracts 4. Identification of targets and mechanism of activity of plant extracts 5. Production and genomic characterization of medicinal plants biomass 6. Chemistry and biochemistry of bioactive natural products of plant origin 7. Critical reviews of the historical, clinical and legal status of medicinal plants, and accounts on topical issues.