胰石蛋白水平比其他生物标志物更早准确预测各种原因的脓毒症的严重程度

IF 1.9 4区生物学 Q4 BIOCHEMICAL RESEARCH METHODS

Journal of microbiological methods Pub Date : 2025-04-08 DOI:10.1016/j.mimet.2025.107129

Dimitrios Kouroupis , Charalampos Zarras , Theocharis Koufakis , Maria Terzaki , Panagiotis Pateinakis , Aristeidis Chalvantzis , Konstantina Mpani , Anthi Issa , Prodromos Soukiouroglou , Anastasia Sarvani , Athina Pyrpasopoulou , Michail Doumas , Eleni Vagdatli

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引用次数: 0

摘要

本研究的目的是比较PSP在不同类型脓毒症中的预后价值，以及常见的生物标志物。PSP水平在菌血症和革兰氏阴性脓毒症中较高，与WBC、CRP和PCT预后较差相关（p = 0,006），可能有助于脓毒症的危险分层。

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Pancreatic stone protein levels accurately predict severity in sepsis of various causes earlier than other biomarkers

The aim of this study was to compare the prognostic value of PSP in different types of sepsis, with common biomarkers. PSP levels were higher in bacteremia and Gram-negative sepsis and correlated with worse outcome (p = 0,006) earlier than WBC, CRP and PCT. It may aid for risk stratification in sepsis.

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来源期刊

Journal of microbiological methods 生物-生化研究方法

CiteScore

4.30

自引率

4.50%

发文量

151

审稿时长

29 days

期刊介绍： The Journal of Microbiological Methods publishes scholarly and original articles, notes and review articles. These articles must include novel and/or state-of-the-art methods, or significant improvements to existing methods. Novel and innovative applications of current methods that are validated and useful will also be published. JMM strives for scholarship, innovation and excellence. This demands scientific rigour, the best available methods and technologies, correctly replicated experiments/tests, the inclusion of proper controls, calibrations, and the correct statistical analysis. The presentation of the data must support the interpretation of the method/approach. All aspects of microbiology are covered, except virology. These include agricultural microbiology, applied and environmental microbiology, bioassays, bioinformatics, biotechnology, biochemical microbiology, clinical microbiology, diagnostics, food monitoring and quality control microbiology, microbial genetics and genomics, geomicrobiology, microbiome methods regardless of habitat, high through-put sequencing methods and analysis, microbial pathogenesis and host responses, metabolomics, metagenomics, metaproteomics, microbial ecology and diversity, microbial physiology, microbial ultra-structure, microscopic and imaging methods, molecular microbiology, mycology, novel mathematical microbiology and modelling, parasitology, plant-microbe interactions, protein markers/profiles, proteomics, pyrosequencing, public health microbiology, radioisotopes applied to microbiology, robotics applied to microbiological methods,rumen microbiology, microbiological methods for space missions and extreme environments, sampling methods and samplers, soil and sediment microbiology, transcriptomics, veterinary microbiology, sero-diagnostics and typing/identification.