N-（o-氰芳基）丙烯酰胺与磺酰氯的光催化自由基级联环化

IF 3.6 2区化学 Q1 CHEMISTRY, ORGANIC

Journal of Organic Chemistry Pub Date : 2025-04-02 DOI:10.1021/acs.joc.5c0028810.1021/acs.joc.5c00288

Mei-Jin Gao, Jian-Hong Fan* and Yu Liu*,

引用次数: 0

摘要

本发明公开了一种光氧化催化的 N-(邻氰基芳基)丙烯酰胺与磺酰氯的自由基级联环化反应，用于构建含磺酰基的吡啶并[4,3,2-gh]菲啶。所开发的合成工具可容忍多种磺酰氯发生级联反应，包括磺酰基加成、腈插入和环化反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Photocatalytic Radical Cascade Cyclization of N-(o-Cyanobiaryl)acrylamides with Sulfonyl Chlorides

查看原文本刊更多论文

Photocatalytic Radical Cascade Cyclization of N-(o-Cyanobiaryl)acrylamides with Sulfonyl Chlorides

A photoredox-catalyzed radical cascade cyclization of N-(o-cyanobiaryl)acrylamides with sulfonyl chlorides for the construction of sulfonyl-containing pyrido[4,3,2-gh]phenanthridines has been disclosed. The developed synthetic tool tolerates a broad range of sulfonyl chlorides to undergo a cascade sequence, including sulfonyl radical addition, nitrile insertion, and cyclization.

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来源期刊

Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.