氨基取代烷基芳烃与苯并咪唑的电化学选择性C(sp3) -H胺化反应

IF 4.4 2区化学 Q2 CHEMISTRY, APPLIED

Advanced Synthesis & Catalysis Pub Date : 2025-04-10 DOI:10.1002/adsc.202500251

Yu-Wei Jiang, Peng-Zhan Zhang, Xiang Sun, Hui Gao, Pei-Long Wang

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引用次数: 0

摘要

研究了氨基取代烷基烯与苯并咪唑的电化学C(sp3) -H胺化反应。反应表现出良好的选择性，C-H的裂解选择性地发生在苯基位置，而不是氨基的α-位置。原子经济性和阶梯经济性，无催化剂，无外部氧化剂，氢气是该电化学反应的唯一和清洁的副产物。

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Electrochemical Selective Benzylic C(sp3)–H Amination of Amino Group-Substituted Alkylarenes with Benzimidazoles

An electrochemical benzylic C(sp3)–H amination reaction of amino group-substituted alkylarenes with benzimidazoles was developed. The reaction showed good selectivity, and C-H cleavage occurred selectively at the benzylic position other than the α-position of the amino group. Atom- and step-economic, catalyst-free, external oxidant-free, H2 as the only and clean byproduct are the additional characteristics of this electrochemical reaction.

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来源期刊

Advanced Synthesis & Catalysis 化学-应用化学

CiteScore

9.40

自引率

7.40%

发文量

447

审稿时长

1.8 months

期刊介绍： Advanced Synthesis & Catalysis (ASC) is the leading primary journal in organic, organometallic, and applied chemistry. The high impact of ASC can be attributed to the unique focus of the journal, which publishes exciting new results from academic and industrial labs on efficient, practical, and environmentally friendly organic synthesis. While homogeneous, heterogeneous, organic, and enzyme catalysis are key technologies to achieve green synthesis, significant contributions to the same goal by synthesis design, reaction techniques, flow chemistry, and continuous processing, multiphase catalysis, green solvents, catalyst immobilization, and recycling, separation science, and process development are also featured in ASC. The Aims and Scope can be found in the Notice to Authors or on the first page of the table of contents in every issue.