超声引导下前列腺癌活检

IF 12.1 1区医学 Q1 UROLOGY & NEPHROLOGY

Nature Reviews Urology Pub Date : 2025-04-09 DOI:10.1038/s41585-025-01033-7

Maria Chiara Masone

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引用次数: 0

摘要

将磁共振成像（MRI）纳入前列腺癌诊断工作流程，大大提高了临床意义的前列腺癌（定义为Gleason分级组≥2）的检测，但也有一些局限性，例如需要复杂的成像设备，而不是每个机构都可以使用。显微超声具有令人难以置信的高分辨率（70 μm分辨率），可作为前列腺活检MRI的有效替代方法。通过OPTIMUM随机对照试验，评估微超声引导下活检与MRI +常规超声融合引导下活检在未接受活检的男性中检测有临床意义的前列腺癌的非劣效性，研究结果发表在JAMA上。

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Microultrasonography-guided prostate cancer biopsy

The incorporation of magnetic resonance imaging (MRI) into the prostate cancer diagnostic workflow has substantially improved detection of clinically significant prostate cancer (defined as Gleason grade group ≥2) but also has some limitations, such as the need for sophisticated imaging facilities that are not accessible in every institution. Microultrasonography, which has an incredibly high resolution (70-μm resolution), could be a valid alternative to MRI in prostate biopsy.

The OPTIMUM randomized controlled trial was conducted to assess the non-inferiority of microultrasonography-guided biopsy compared with MRI plus conventional ultrasonography fusion-guided biopsy for the detection of clinically significant prostate cancer in biopsy-naive men, and the results were published in JAMA.

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来源期刊

Nature Reviews Urology 医学-泌尿学与肾脏学

CiteScore

12.50

自引率

2.60%

发文量

123

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.